BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_RMUGS_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_RMUGS_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACD adrenocortical dysplasia homolog (mouse)
AKR1C3 aldo-keto reductase family 1, member C3
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
BEX4 brain expressed, X-linked 4
BIRC3 baculoviral IAP repeat containing 3
CA2 carbonic anhydrase II
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD99 CD99 molecule
CDK14 cyclin-dependent kinase 14
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CNN3 calponin 3, acidic
COL11A1 collagen, type XI, alpha 1
CPE carboxypeptidase E
ENOPH1 enolase-phosphatase 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FGFR3 fibroblast growth factor receptor 3
FHOD3 formin homology 2 domain containing 3
FOXF2 forkhead box F2
GCLM glutamate-cysteine ligase, modifier subunit
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KRT19 keratin 19, type I
LTBP2 latent transforming growth factor beta binding protein 2
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MXRA5 matrix-remodelling associated 5
NQO2 NAD(P)H dehydrogenase, quinone 2
OLFM1 olfactomedin 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RHOBTB3 Rho-related BTB domain containing 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SC5D sterol-C5-desaturase
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SPRED2 sprouty-related, EVH1 domain containing 2
STS steroid sulfatase (microsomal), isozyme S
SULF1 sulfatase 1
TRIB3 tribbles pseudokinase 3
TXNRD1 thioredoxin reductase 1
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ARID4B AT rich interactive domain 4B (RBP1-like)
BASP1 brain abundant, membrane attached signal protein 1
C2CD5 C2 calcium-dependent domain containing 5
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CSRP1 cysteine and glycine-rich protein 1
CTSC cathepsin C
DACH1 dachshund family transcription factor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ETNK1 ethanolamine kinase 1
GOLGA8A golgin A8 family, member A
GOLGA8H golgin A8 family, member H
GSN gelsolin
HDGFRP3 hepatoma-derived growth factor, related protein 3
IQCG IQ motif containing G
ITGA7 integrin, alpha 7
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTF lactotransferrin
MAGED1 melanoma antigen family D1
NMT2 N-myristoyltransferase 2
NUP98 nucleoporin 98kDa
OLFM4 olfactomedin 4
PHYH phytanoyl-CoA 2-hydroxylase
PLA2G16 phospholipase A2, group XVI
PLCB4 phospholipase C, beta 4
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTX3 pentraxin 3, long
PUF60 poly-U binding splicing factor 60KDa
QDPR quinoid dihydropteridine reductase
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SFRP1 secreted frizzled-related protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)