BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKAP13 A kinase (PRKA) anchor protein 13
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BAG3 BCL2-associated athanogene 3
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CALML5 calmodulin-like 5
CD163 CD163 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL10 chemokine (C-X-C motif) ligand 10
DDIT4 DNA-damage-inducible transcript 4
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOLR1 folate receptor 1 (adult)
FOXO1 forkhead box O1
GCLM glutamate-cysteine ligase, modifier subunit
GJA1 gap junction protein, alpha 1, 43kDa
GUSBP3 glucuronidase, beta pseudogene 3
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPB8 heat shock 22kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IL1R2 interleukin 1 receptor, type II
ITM2A integral membrane protein 2A
JUN jun proto-oncogene
MAST2 microtubule associated serine/threonine kinase 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
P3H2 prolyl 3-hydroxylase 2
PIR pirin (iron-binding nuclear protein)
PLBD1 phospholipase B domain containing 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RHCG Rh family, C glycoprotein
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SPARCL1 SPARC-like 1 (hevin)
TAC1 tachykinin, precursor 1
VSIG4 V-set and immunoglobulin domain containing 4
VWF von Willebrand factor

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA1 annexin A1
ARHGAP29 Rho GTPase activating protein 29
ASPH aspartate beta-hydroxylase
CIAPIN1 cytokine induced apoptosis inhibitor 1
CLDN3 claudin 3
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CTBP2 C-terminal binding protein 2
CYR61 cysteine-rich, angiogenic inducer, 61
DDAH1 dimethylarginine dimethylaminohydrolase 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EGFR epidermal growth factor receptor
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FHL1 four and a half LIM domains 1
FSTL1 follistatin-like 1
G0S2 G0/G1 switch 2
GPX1 glutathione peroxidase 1
HOXA10 homeobox A10
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
LGALS1 lectin, galactoside-binding, soluble, 1
MSN moesin
OLFM4 olfactomedin 4
PCCB propionyl CoA carboxylase, beta polypeptide
PLAUR plasminogen activator, urokinase receptor
PXDC1 PX domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SDC4 syndecan 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRY2 sprouty homolog 2 (Drosophila)
TFF1 trefoil factor 1
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TJP2 tight junction protein 2
TNC tenascin C
TXNDC9 thioredoxin domain containing 9
VCAN versican
VIM vimentin
XPO7 exportin 7