BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_MDST8_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

119 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_MDST8_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD4 abhydrolase domain containing 4
ACTA1 actin, alpha 1, skeletal muscle
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANGPT1 angiopoietin 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
CA12 carbonic anhydrase XII
CCDC86 coiled-coil domain containing 86
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CKM creatine kinase, muscle
CNPY3 canopy FGF signaling regulator 3
CRYAB crystallin, alpha B
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CXCL5 chemokine (C-X-C motif) ligand 5
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF1 eukaryotic translation initiation factor 1
FAM46A family with sequence similarity 46, member A
FBXO11 F-box protein 11
FKBP11 FK506 binding protein 11, 19 kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
GCLM glutamate-cysteine ligase, modifier subunit
GSTA4 glutathione S-transferase alpha 4
HMOX1 heme oxygenase 1
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGHM immunoglobulin heavy constant mu
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITM2C integral membrane protein 2C
LMO4 LIM domain only 4
LOX lysyl oxidase
MBP myelin basic protein
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP3 matrix metallopeptidase 3
MYBPC1 myosin binding protein C, slow type
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NQO1 NAD(P)H dehydrogenase, quinone 1
NRCAM neuronal cell adhesion molecule
P3H2 prolyl 3-hydroxylase 2
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
RPS5 ribosomal protein S5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLN sarcolipin
TNNC2 troponin C type 2 (fast)
TNNT1 troponin T type 1 (skeletal, slow)
TTN titin
VAV3 vav 3 guanine nucleotide exchange factor
VLDLR very low density lipoprotein receptor

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADAMDEC1 ADAM-like, decysin 1
ADCY1 adenylate cyclase 1 (brain)
AIM1 absent in melanoma 1
AKAP12 A kinase (PRKA) anchor protein 12
ALCAM activated leukocyte cell adhesion molecule
ANPEP alanyl (membrane) aminopeptidase
APLP2 amyloid beta (A4) precursor-like protein 2
BASP1 brain abundant, membrane attached signal protein 1
CAST calpastatin
CCND2 cyclin D2
CCNE2 cyclin E2
CD27 CD27 molecule
CD9 CD9 molecule
COL10A1 collagen, type X, alpha 1
CPE carboxypeptidase E
CXCL14 chemokine (C-X-C motif) ligand 14
DOCK9 dedicator of cytokinesis 9
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FABP4 fatty acid binding protein 4, adipocyte
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
GADD45B growth arrest and DNA-damage-inducible, beta
GREM1 gremlin 1, DAN family BMP antagonist
HOXC6 homeobox C6
LAMC2 laminin, gamma 2
LAPTM5 lysosomal protein transmembrane 5
LTBP1 latent transforming growth factor beta binding protein 1
MAPT microtubule-associated protein tau
MGP matrix Gla protein
NAV2 neuron navigator 2
NFIB nuclear factor I/B
NOTCH2 notch 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAN2 PAN2 poly(A) specific ribonuclease subunit
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBX3 pre-B-cell leukemia homeobox 3
PCDH9 protocadherin 9
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PON2 paraoxonase 2
POSTN periostin, osteoblast specific factor
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSD3 pleckstrin and Sec7 domain containing 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SCNN1B sodium channel, non voltage gated 1 beta subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SORBS2 sorbin and SH3 domain containing 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TACSTD2 tumor-associated calcium signal transducer 2
TBC1D16 TBC1 domain family, member 16
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TNC tenascin C
TNS1 tensin 1
TSPYL5 TSPY-like 5
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZBTB16 zinc finger and BTB domain containing 16