BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
ADORA2B adenosine A2b receptor
AKR1C1 aldo-keto reductase family 1, member C1
BAG3 BCL2-associated athanogene 3
BLVRB biliverdin reductase B
C1QA complement component 1, q subcomponent, A chain
CD163 CD163 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLGN calmegin
CLU clusterin
COL4A5 collagen, type IV, alpha 5
CSTA cystatin A (stefin A)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ELOVL6 ELOVL fatty acid elongase 6
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GLUL glutamate-ammonia ligase
HBB hemoglobin, beta
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGHD immunoglobulin heavy constant delta
IGKV1-5 immunoglobulin kappa variable 1-5
IL1R2 interleukin 1 receptor, type II
JAG1 jagged 1
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KRT13 keratin 13, type I
KRT6A keratin 6A, type II
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MT1F metallothionein 1F
MT1X metallothionein 1X
NQO1 NAD(P)H dehydrogenase, quinone 1
OXSR1 oxidative stress responsive 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PGD phosphogluconate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLBD1 phospholipase B domain containing 1
PLIN2 perilipin 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
S100A2 S100 calcium binding protein A2
SFN stratifin
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPRR3 small proline-rich protein 3
STK10 serine/threonine kinase 10
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM16 tripartite motif containing 16
TXN thioredoxin
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ARID5B AT rich interactive domain 5B (MRF1-like)
B3GNT1
BICC1 BicC family RNA binding protein 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DEPTOR DEP domain containing MTOR-interacting protein
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIST1H4C histone cluster 1, H4c
HOXA5 homeobox A5
MYB v-myb avian myeloblastosis viral oncogene homolog
NFIB nuclear factor I/B
NREP neuronal regeneration related protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFC platelet derived growth factor C
PEG10 paternally expressed 10
RGS2 regulator of G-protein signaling 2
SOX4 SRY (sex determining region Y)-box 4
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS2 thrombospondin 2
TSPAN8 tetraspanin 8
VCAN versican