BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BAG3 BCL2-associated athanogene 3
C1QB complement component 1, q subcomponent, B chain
CD14 CD14 molecule
CD9 CD9 molecule
CTSL cathepsin L
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DSC2 desmocollin 2
DSG3 desmoglein 3
FGFBP1 fibroblast growth factor binding protein 1
FOSL1 FOS-like antigen 1
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
KDM5D lysine (K)-specific demethylase 5D
KRT13 keratin 13, type I
LAPTM5 lysosomal protein transmembrane 5
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NQO1 NAD(P)H dehydrogenase, quinone 1
PERP PERP, TP53 apoptosis effector
PIR pirin (iron-binding nuclear protein)
RPS4Y1 ribosomal protein S4, Y-linked 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPP1 secreted phosphoprotein 1
TKT transketolase
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGTR1 angiotensin II receptor, type 1
AOX1 aldehyde oxidase 1
APOD apolipoprotein D
AREG amphiregulin
CFH complement factor H
COL14A1 collagen, type XIV, alpha 1
CXCL2 chemokine (C-X-C motif) ligand 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ERAP1 endoplasmic reticulum aminopeptidase 1
FHL1 four and a half LIM domains 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HES1 hes family bHLH transcription factor 1
HNMT histamine N-methyltransferase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MYH10 myosin, heavy chain 10, non-muscle
NAV2 neuron navigator 2
POSTN periostin, osteoblast specific factor
PTGDS prostaglandin D2 synthase 21kDa (brain)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFRP1 secreted frizzled-related protein 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
STOM stomatin
TESC tescalcin
TFRC transferrin receptor
TLE4 transducin-like enhancer of split 4
TM4SF4 transmembrane 4 L six family member 4
TNS3 tensin 3
TSPAN8 tetraspanin 8
XIST X inactive specific transcript (non-protein coding)