BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_HCC15_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

110 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_HCC15_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ACAA2 acetyl-CoA acyltransferase 2
ADGRF5 adhesion G protein-coupled receptor F5
ASPN asporin
ATF3 activating transcription factor 3
ATP11B ATPase, class VI, type 11B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
C3ORF14 chromosome 3 open reading frame 14
CD200 CD200 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CECR1 cat eye syndrome chromosome region, candidate 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLCA4 chloride channel accessory 4
CNPY3 canopy FGF signaling regulator 3
COL4A5 collagen, type IV, alpha 5
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CRISP3 cysteine-rich secretory protein 3
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ERBB2 erb-b2 receptor tyrosine kinase 2
FAM69A family with sequence similarity 69, member A
GATA3 GATA binding protein 3
GUSBP11 glucuronidase, beta pseudogene 11
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
ITM2C integral membrane protein 2C
KRT19 keratin 19, type I
KRT23 keratin 23, type I
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
ORC1 origin recognition complex, subunit 1
PCP4 Purkinje cell protein 4
PIP prolactin-induced protein
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PON3 paraoxonase 3
PXDN peroxidasin
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SCPEP1 serine carboxypeptidase 1
SDC1 syndecan 1
SPON2 spondin 2, extracellular matrix protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STON1 stonin 1
TCEA2 transcription elongation factor A (SII), 2
TCL1A T-cell leukemia/lymphoma 1A
UGP2 UDP-glucose pyrophosphorylase 2
VTCN1 V-set domain containing T cell activation inhibitor 1
YBX3 Y box binding protein 3

decreased expression

Symbol Name
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BST2 bone marrow stromal cell antigen 2
C6ORF48 chromosome 6 open reading frame 48
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CRIP1 cysteine-rich protein 1 (intestinal)
CST3 cystatin C
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMP3 epithelial membrane protein 3
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO11 F-box protein 11
GANAB glucosidase, alpha; neutral AB
GSTM3 glutathione S-transferase mu 3 (brain)
GSTP1 glutathione S-transferase pi 1
HOXC6 homeobox C6
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LARS leucyl-tRNA synthetase
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MET MET proto-oncogene, receptor tyrosine kinase
MSX1 msh homeobox 1
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
PDGFC platelet derived growth factor C
PTGES prostaglandin E synthase
RBP1 retinol binding protein 1, cellular
RPS26 ribosomal protein S26
S100A2 S100 calcium binding protein A2
S100A6 S100 calcium binding protein A6
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SORBS3 sorbin and SH3 domain containing 3
SORD sorbitol dehydrogenase
SRPX sushi-repeat containing protein, X-linked
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF3 trefoil factor 3 (intestinal)
WBSCR22 Williams Beuren syndrome chromosome region 22