BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

122 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP11B ATPase, class VI, type 11B
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAG3 BCL2-associated athanogene 3
C10ORF10 chromosome 10 open reading frame 10
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHI3L2 chitinase 3-like 2
CXCL10 chemokine (C-X-C motif) ligand 10
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ELOVL5 ELOVL fatty acid elongase 5
FAM129A family with sequence similarity 129, member A
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GADD45A growth arrest and DNA-damage-inducible, alpha
GAL galanin/GMAP prepropeptide
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GLUL glutamate-ammonia ligase
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IDO1 indoleamine 2,3-dioxygenase 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KLHL21 kelch-like family member 21
LGALS8 lectin, galactoside-binding, soluble, 8
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NES nestin
NPC1 Niemann-Pick disease, type C1
NQO1 NAD(P)H dehydrogenase, quinone 1
NUPR1 nuclear protein, transcriptional regulator, 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PIR pirin (iron-binding nuclear protein)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARD peroxisome proliferator-activated receptor delta
RIOK3 RIO kinase 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
TKT transketolase
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADD3 adducin 3 (gamma)
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDOB aldolase B, fructose-bisphosphate
APOLD1 apolipoprotein L domain containing 1
AREG amphiregulin
ATF5 activating transcription factor 5
CAST calpastatin
CBX3 chromobox homolog 3
CCND1 cyclin D1
CCNF cyclin F
COL14A1 collagen, type XIV, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CYBA cytochrome b-245, alpha polypeptide
CYTH1 cytohesin 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DPYSL2 dihydropyrimidinase-like 2
ELF1 E74-like factor 1 (ets domain transcription factor)
FBLN1 fibulin 1
GREM1 gremlin 1, DAN family BMP antagonist
HOXA10 homeobox A10
HOXA5 homeobox A5
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP4 insulin-like growth factor binding protein 4
IRS2 insulin receptor substrate 2
KRT8 keratin 8, type II
LAMP5 lysosomal-associated membrane protein family, member 5
LOXL1 lysyl oxidase-like 1
LXN latexin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MFAP5 microfibrillar associated protein 5
NFIB nuclear factor I/B
NR2F6 nuclear receptor subfamily 2, group F, member 6
OLFM4 olfactomedin 4
PAN2 PAN2 poly(A) specific ribonuclease subunit
PRSS3 protease, serine, 3
RPS11 ribosomal protein S11
SCAND1 SCAN domain containing 1
SKAP2 src kinase associated phosphoprotein 2
SOX4 SRY (sex determining region Y)-box 4
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THAP11 THAP domain containing 11
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TP53I3 tumor protein p53 inducible protein 3
VCAN versican
ZCCHC24 zinc finger, CCHC domain containing 24
ZFPM2 zinc finger protein, FOG family member 2