BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-K61033289_15-Deoxy-?12,14-prostaglandin J2_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JUN jun proto-oncogene
PIR pirin (iron-binding nuclear protein)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AURKA aurora kinase A
CCND1 cyclin D1
CCNF cyclin F
FST follistatin
MAGEA12 melanoma antigen family A12
MAGEA6 melanoma antigen family A6
MOK MOK protein kinase
NRN1 neuritin 1
PRSS23 protease, serine, 23
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SMAD3 SMAD family member 3
TMEM2 transmembrane protein 2
TNC tenascin C