BRD-K60866521_idelalisib_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K60866521_idelalisib_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
CD14 CD14 molecule
CTSB cathepsin B
CXCL10 chemokine (C-X-C motif) ligand 10
DLK1 delta-like 1 homolog (Drosophila)
EPHB2 EPH receptor B2
GEM GTP binding protein overexpressed in skeletal muscle
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HBB hemoglobin, beta
HIST1H2AC histone cluster 1, H2ac
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
LEF1 lymphoid enhancer-binding factor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MUC1 mucin 1, cell surface associated
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLAGL1 pleiomorphic adenoma gene-like 1
PPAP2B phosphatidic acid phosphatase type 2B
PROS1 protein S (alpha)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A7 S100 calcium binding protein A7
S100B S100 calcium binding protein B
SEPP1 selenoprotein P, plasma, 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIB2 tribbles pseudokinase 2
TSPAN13 tetraspanin 13
TXNIP thioredoxin interacting protein
VNN1 vanin 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
AHNAK2 AHNAK nucleoprotein 2
ANXA1 annexin A1
BEX1 brain expressed, X-linked 1
CXCL5 chemokine (C-X-C motif) ligand 5
HSPH1 heat shock 105kDa/110kDa protein 1
ITGB1BP1 integrin beta 1 binding protein 1
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MDFIC MyoD family inhibitor domain containing
MFAP5 microfibrillar associated protein 5
MKNK2 MAP kinase interacting serine/threonine kinase 2
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
TACSTD2 tumor-associated calcium signal transducer 2
TNIP1 TNFAIP3 interacting protein 1
TUBB6 tubulin, beta 6 class V
YBX3 Y box binding protein 3
ZMYM2 zinc finger, MYM-type 2