BRD-K60298136_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K60298136_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ANPEP alanyl (membrane) aminopeptidase
BAZ1A bromodomain adjacent to zinc finger domain, 1A
C5AR1 complement component 5a receptor 1
CCNE2 cyclin E2
CD52 CD52 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLEC11A C-type lectin domain family 11, member A
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTH1 cytohesin 1
DIO1 deiodinase, iodothyronine, type I
DUSP6 dual specificity phosphatase 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP3 epithelial membrane protein 3
F13A1 coagulation factor XIII, A1 polypeptide
FOSL1 FOS-like antigen 1
HES1 hes family bHLH transcription factor 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
JUN jun proto-oncogene
KYNU kynureninase
MARCKS myristoylated alanine-rich protein kinase C substrate
MSX1 msh homeobox 1
PDLIM5 PDZ and LIM domain 5
PNMA1 paraneoplastic Ma antigen 1
PROM1 prominin 1
RAP1GAP RAP1 GTPase activating protein
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SORBS3 sorbin and SH3 domain containing 3
THBS1 thrombospondin 1
TMEM2 transmembrane protein 2
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AREG amphiregulin
ATP11B ATPase, class VI, type 11B
AUTS2 autism susceptibility candidate 2
CADM1 cell adhesion molecule 1
CCND2 cyclin D2
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CORO1A coronin, actin binding protein, 1A
DES desmin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DMD dystrophin
FAM129A family with sequence similarity 129, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FXYD3 FXYD domain containing ion transport regulator 3
FZD7 frizzled class receptor 7
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IPO13 importin 13
IVNS1ABP influenza virus NS1A binding protein
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT19 keratin 19, type I
MCAM melanoma cell adhesion molecule
MGP matrix Gla protein
MOXD1 monooxygenase, DBH-like 1
P3H2 prolyl 3-hydroxylase 2
PAM peptidylglycine alpha-amidating monooxygenase
PEG10 paternally expressed 10
PRDX2 peroxiredoxin 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SORBS1 sorbin and SH3 domain containing 1
SPRY2 sprouty homolog 2 (Drosophila)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TPSAB1 tryptase alpha/beta 1
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
TSPAN13 tetraspanin 13
ZNF395 zinc finger protein 395