BRD-K60202068_N-(2-(4-(2-hydroxyethylamino)-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide wh-gc-round5-31_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K60202068_N-(2-(4-(2-hydroxyethylamino)-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide wh-gc-round5-31_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AURKB aurora kinase B
C1QA complement component 1, q subcomponent, A chain
CD93 CD93 molecule
CORO1A coronin, actin binding protein, 1A
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DKK3 dickkopf WNT signaling pathway inhibitor 3
FBXL12 F-box and leucine-rich repeat protein 12
FHOD3 formin homology 2 domain containing 3
FXYD6 FXYD domain containing ion transport regulator 6
G0S2 G0/G1 switch 2
IFI16 interferon, gamma-inducible protein 16
KCTD12 potassium channel tetramerization domain containing 12
MMP9 matrix metallopeptidase 9
NES nestin
PECAM1 platelet/endothelial cell adhesion molecule 1
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
RGCC regulator of cell cycle
SPARCL1 SPARC-like 1 (hevin)
TYROBP TYRO protein tyrosine kinase binding protein

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ANKRD10 ankyrin repeat domain 10
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CA12 carbonic anhydrase XII
CEMIP cell migration inducing protein, hyaluronan binding
CHPT1 choline phosphotransferase 1
CLCN3 chloride channel, voltage-sensitive 3
COCH cochlin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP1 dual specificity phosphatase 1
GLRX glutaredoxin (thioltransferase)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
PLS1 plastin 1
PSD3 pleckstrin and Sec7 domain containing 3
RPS27L ribosomal protein S27-like
TIMP3 TIMP metallopeptidase inhibitor 3
UGCG UDP-glucose ceramide glucosyltransferase