BRD-K60174629_Z-prolyl-prolinal_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K60174629_Z-prolyl-prolinal_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BEX4 brain expressed, X-linked 4
DCN decorin
DUOX2 dual oxidase 2
GSTM3 glutathione S-transferase mu 3 (brain)
IGHD immunoglobulin heavy constant delta
IL32 interleukin 32
INSM1 insulinoma-associated 1
MEX3D mex-3 RNA binding family member D
MT1X metallothionein 1X
PLIN2 perilipin 2
PLTP phospholipid transfer protein
REG3A regenerating islet-derived 3 alpha
RGS5 regulator of G-protein signaling 5
SIRT3 sirtuin 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST18 suppression of tumorigenicity 18, zinc finger

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
AQP3 aquaporin 3 (Gill blood group)
CCL20 chemokine (C-C motif) ligand 20
CTSL cathepsin L
CXCL8 chemokine (C-X-C motif) ligand 8
FGF13 fibroblast growth factor 13
GDF15 growth differentiation factor 15
HOXB7 homeobox B7
HOXC6 homeobox C6
LAPTM4B lysosomal protein transmembrane 4 beta
LRP10 low density lipoprotein receptor-related protein 10
LTBP1 latent transforming growth factor beta binding protein 1
NAAA N-acylethanolamine acid amidase
POSTN periostin, osteoblast specific factor
PRR7 proline rich 7 (synaptic)
SIDT2 SID1 transmembrane family, member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TPM1 tropomyosin 1 (alpha)
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5
WSB2 WD repeat and SOCS box containing 2
ZMYM2 zinc finger, MYM-type 2