BRD-K60067222_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

108 genes differentially expressed following the BRD-K60067222_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACKR3 atypical chemokine receptor 3
ACTG2 actin, gamma 2, smooth muscle, enteric
ADIRF adipogenesis regulatory factor
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANGPTL2 angiopoietin-like 2
APOLD1 apolipoprotein L domain containing 1
BGN biglycan
CAPG capping protein (actin filament), gelsolin-like
CCR1 chemokine (C-C motif) receptor 1
CD14 CD14 molecule
CD93 CD93 molecule
CD99 CD99 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CECR1 cat eye syndrome chromosome region, candidate 1
CES1 carboxylesterase 1
CHRDL1 chordin-like 1
COLEC12 collectin sub-family member 12
CREM cAMP responsive element modulator
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTBP2 C-terminal binding protein 2
DES desmin
DIXDC1 DIX domain containing 1
EDNRA endothelin receptor type A
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMP1 epithelial membrane protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FCGBP Fc fragment of IgG binding protein
FHL1 four and a half LIM domains 1
FXYD6 FXYD domain containing ion transport regulator 6
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HOXA10 homeobox A10
HPSE heparanase
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP5 insulin-like growth factor binding protein 5
IVNS1ABP influenza virus NS1A binding protein
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LCN2 lipocalin 2
LPAR6 lysophosphatidic acid receptor 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCTP1 multiple C2 domains, transmembrane 1
MGP matrix Gla protein
MN1 meningioma (disrupted in balanced translocation) 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MTMR11 myotubularin related protein 11
MXRA5 matrix-remodelling associated 5
NGRN neugrin, neurite outgrowth associated
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OLFM4 olfactomedin 4
OSR2 odd-skipped related transciption factor 2
PALLD palladin, cytoskeletal associated protein
PALMD palmdelphin
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM3 PDZ and LIM domain 3
PDZRN3 PDZ domain containing ring finger 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PLAU plasminogen activator, urokinase
PLN phospholamban
PPT1 palmitoyl-protein thioesterase 1
PRKCH protein kinase C, eta
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RCAN2 regulator of calcineurin 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS2 regulator of G-protein signaling 2
RIN2 Ras and Rab interactor 2
STON1 stonin 1
SULF1 sulfatase 1
SVIL supervillin
TLR4 toll-like receptor 4
TMEM106C transmembrane protein 106C
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRDV3 T cell receptor delta variable 3
TSPAN8 tetraspanin 8
WLS wntless Wnt ligand secretion mediator

decreased expression

Symbol Name
AIM2 absent in melanoma 2
ALCAM activated leukocyte cell adhesion molecule
CCL19 chemokine (C-C motif) ligand 19
CCL21 chemokine (C-C motif) ligand 21
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
DHRS2 dehydrogenase/reductase (SDR family) member 2
EIF5B eukaryotic translation initiation factor 5B
FAM46A family with sequence similarity 46, member A
FASTKD5 FAST kinase domains 5
GOLGA8A golgin A8 family, member A
IGHM immunoglobulin heavy constant mu
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
OXTR oxytocin receptor
PRAME preferentially expressed antigen in melanoma
RBM25 RNA binding motif protein 25
SEPP1 selenoprotein P, plasma, 1
SPEN spen family transcriptional repressor
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TCL1A T-cell leukemia/lymphoma 1A
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI2 tissue factor pathway inhibitor 2
TXNDC9 thioredoxin domain containing 9
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble