BRD-K58772419_AZD-6482_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

46 genes differentially expressed following the BRD-K58772419_AZD-6482_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
APOD apolipoprotein D
BCL6 B-cell CLL/lymphoma 6
BID BH3 interacting domain death agonist
BLNK B-cell linker
C10ORF10 chromosome 10 open reading frame 10
CFD complement factor D (adipsin)
DCN decorin
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
FAM3C family with sequence similarity 3, member C
FZD1 frizzled class receptor 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
METTL7A methyltransferase like 7A
MGP matrix Gla protein
PALMD palmdelphin
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
TCF4 transcription factor 4
TGFBI transforming growth factor, beta-induced, 68kDa
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
VAV3 vav 3 guanine nucleotide exchange factor

decreased expression

Symbol Name
AMD1 adenosylmethionine decarboxylase 1
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
CD24 CD24 molecule
CTSZ cathepsin Z
DMBT1 deleted in malignant brain tumors 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
EFNB2 ephrin-B2
FOSL1 FOS-like antigen 1
GBP1 guanylate binding protein 1, interferon-inducible
HBEGF heparin-binding EGF-like growth factor
JMJD6 jumonji domain containing 6
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT6B keratin 6B, type II
MAT2A methionine adenosyltransferase II, alpha
S100A7 S100 calcium binding protein A7
SFN stratifin
SPP1 secreted phosphoprotein 1
TPBG trophoblast glycoprotein