BRD-K58479490_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K58479490_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARMCX2 armadillo repeat containing, X-linked 2
BLNK B-cell linker
CAV1 caveolin 1, caveolae protein, 22kDa
CD9 CD9 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COL11A1 collagen, type XI, alpha 1
COL15A1 collagen, type XV, alpha 1
DDIT4 DNA-damage-inducible transcript 4
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GREM1 gremlin 1, DAN family BMP antagonist
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
LRRC15 leucine rich repeat containing 15
MMP1 matrix metallopeptidase 1
MXRA5 matrix-remodelling associated 5
NLGN4X neuroligin 4, X-linked
NUPR1 nuclear protein, transcriptional regulator, 1
PCDH7 protocadherin 7
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TPBG trophoblast glycoprotein
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
C2CD5 C2 calcium-dependent domain containing 5
CD151 CD151 molecule (Raph blood group)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHPT1 choline phosphotransferase 1
CLU clusterin
COCH cochlin
CST3 cystatin C
FHL2 four and a half LIM domains 2
PCDH9 protocadherin 9
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRKCA protein kinase C, alpha
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRGN serglycin
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
TOX3 TOX high mobility group box family member 3