BRD-K58214070_N-{3-[(2-Chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K58214070_N-{3-[(2-Chloro-acetyl)-(4-nitro-phenyl)-amino]-propyl}-2,2,2-trifluoro-acetamide_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APOD apolipoprotein D
ASCL1 achaete-scute family bHLH transcription factor 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CCL20 chemokine (C-C motif) ligand 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CTSL cathepsin L
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
FTH1 ferritin, heavy polypeptide 1
HMOX1 heme oxygenase 1
KCNK1 potassium channel, two pore domain subfamily K, member 1
KYNU kynureninase
LBH limb bud and heart development
MALL mal, T-cell differentiation protein-like
MBP myelin basic protein
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MT1X metallothionein 1X
MUC4 mucin 4, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
NQO1 NAD(P)H dehydrogenase, quinone 1
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRL platelet-derived growth factor receptor-like
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAU plasminogen activator, urokinase
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
SRSF6 serine/arginine-rich splicing factor 6
TACC2 transforming, acidic coiled-coil containing protein 2
TFF3 trefoil factor 3 (intestinal)
TGFA transforming growth factor, alpha

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
BST2 bone marrow stromal cell antigen 2
CD52 CD52 molecule
EMP3 epithelial membrane protein 3
GATA2 GATA binding protein 2
H1FX H1 histone family, member X
HIST1H2BG histone cluster 1, H2bg
IFITM1 interferon induced transmembrane protein 1
IVNS1ABP influenza virus NS1A binding protein
KIAA0101 KIAA0101
LOXL1 lysyl oxidase-like 1
LTBP1 latent transforming growth factor beta binding protein 1
NPY1R neuropeptide Y receptor Y1
PBLD phenazine biosynthesis-like protein domain containing
PCNA proliferating cell nuclear antigen
PDGFC platelet derived growth factor C
POSTN periostin, osteoblast specific factor
RELN reelin
RGS2 regulator of G-protein signaling 2
RPA3 replication protein A3, 14kDa
TM4SF1 transmembrane 4 L six family member 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VNN1 vanin 1