BRD-K57930080_4-(3,4-dimethoxyphenyl)pyridine hydrobromide WG-7_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K57930080_4-(3,4-dimethoxyphenyl)pyridine hydrobromide WG-7_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AUTS2 autism susceptibility candidate 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
COL5A1 collagen, type V, alpha 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
DLG5 discs, large homolog 5 (Drosophila)
DUSP1 dual specificity phosphatase 1
EPAS1 endothelial PAS domain protein 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
GPM6A glycoprotein M6A
GPR183 G protein-coupled receptor 183
IDO1 indoleamine 2,3-dioxygenase 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KIF5C kinesin family member 5C
KLK5 kallikrein-related peptidase 5
LDOC1 leucine zipper, down-regulated in cancer 1
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MMP9 matrix metallopeptidase 9
MXRA7 matrix-remodelling associated 7
PCOLCE procollagen C-endopeptidase enhancer
PDE4B phosphodiesterase 4B, cAMP-specific
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PDZD2 PDZ domain containing 2
PENK proenkephalin
PMP22 peripheral myelin protein 22
PRKCQ protein kinase C, theta
PTN pleiotrophin
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGS1 regulator of G-protein signaling 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCD5 stearoyl-CoA desaturase 5
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SMYD3 SET and MYND domain containing 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SULF1 sulfatase 1
TARP TCR gamma alternate reading frame protein
TMSB15A thymosin beta 15a
TPST2 tyrosylprotein sulfotransferase 2
TRIM13 tripartite motif containing 13

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BZW2 basic leucine zipper and W2 domains 2
CAST calpastatin
CD24 CD24 molecule
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS2 dehydrogenase/reductase (SDR family) member 2
EIF5B eukaryotic translation initiation factor 5B
EMP1 epithelial membrane protein 1
FABP7 fatty acid binding protein 7, brain
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLIPR1 GLI pathogenesis-related 1
HES1 hes family bHLH transcription factor 1
IL1R1 interleukin 1 receptor, type I
KRT15 keratin 15, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
MBD2 methyl-CpG binding domain protein 2
METTL7A methyltransferase like 7A
MPO myeloperoxidase
NCALD neurocalcin delta
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCSK1 proprotein convertase subtilisin/kexin type 1
PSCA prostate stem cell antigen
QPCT glutaminyl-peptide cyclotransferase
RNF167 ring finger protein 167
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPINK1 serine peptidase inhibitor, Kazal type 1
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TPD52 tumor protein D52
TXNDC9 thioredoxin domain containing 9
TXNL1 thioredoxin-like 1
UGDH UDP-glucose 6-dehydrogenase