BRD-K57282030_JW-7-24-1_LNCAP_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K57282030_JW-7-24-1_LNCAP_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCK3 aarF domain containing kinase 3
APOA2 apolipoprotein A-II
CAPN1 calpain 1, (mu/I) large subunit
CD9 CD9 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CLU clusterin
CPVL carboxypeptidase, vitellogenic-like
CRYAB crystallin, alpha B
CST3 cystatin C
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FGF13 fibroblast growth factor 13
FOXC1 forkhead box C1
GLUL glutamate-ammonia ligase
GOLGA8A golgin A8 family, member A
GPC3 glypican 3
HP haptoglobin
INSIG1 insulin induced gene 1
JAG1 jagged 1
LPIN1 lipin 1
MT1X metallothionein 1X
NPC1 Niemann-Pick disease, type C1
NRIP1 nuclear receptor interacting protein 1
PERP PERP, TP53 apoptosis effector
PLAGL1 pleiomorphic adenoma gene-like 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RRAGD Ras-related GTP binding D
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SCYL3 SCY1-like 3 (S. cerevisiae)
SEPP1 selenoprotein P, plasma, 1
SETBP1 SET binding protein 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TPSB2 tryptase beta 2 (gene/pseudogene)
TXNIP thioredoxin interacting protein
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ANXA3 annexin A3
AREG amphiregulin
ASS1 argininosuccinate synthase 1
BASP1 brain abundant, membrane attached signal protein 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD40 CD40 molecule, TNF receptor superfamily member 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL10 chemokine (C-X-C motif) ligand 10
DDIT4 DNA-damage-inducible transcript 4
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOLR1 folate receptor 1 (adult)
GBP1 guanylate binding protein 1, interferon-inducible
GIMAP4 GTPase, IMAP family member 4
HOXB7 homeobox B7
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL32 interleukin 32
IRF8 interferon regulatory factor 8
KLK10 kallikrein-related peptidase 10
KLK11 kallikrein-related peptidase 11
MAT2A methionine adenosyltransferase II, alpha
MMP11 matrix metallopeptidase 11
MMP12 matrix metallopeptidase 12
MSLN mesothelin
MSMB microseminoprotein, beta-
MYH10 myosin, heavy chain 10, non-muscle
NNMT nicotinamide N-methyltransferase
PALLD palladin, cytoskeletal associated protein
PHLDA2 pleckstrin homology-like domain, family A, member 2
PRSS3 protease, serine, 3
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RHOBTB3 Rho-related BTB domain containing 3
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SNAP25 synaptosomal-associated protein, 25kDa
SRGN serglycin
SST somatostatin
STAT1 signal transducer and activator of transcription 1, 91kDa
TST thiosulfate sulfurtransferase (rhodanese)