BRD-K57080016_-666_HEPG2_6.0_h_80.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K57080016_-666_HEPG2_6.0_h_80.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
CAST calpastatin
CCND2 cyclin D2
CCNG1 cyclin G1
COL4A5 collagen, type IV, alpha 5
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DMD dystrophin
FGFR3 fibroblast growth factor receptor 3
FKBP11 FK506 binding protein 11, 19 kDa
MAGEA3 melanoma antigen family A3
METTL7A methyltransferase like 7A
NPY1R neuropeptide Y receptor Y1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TBX2 T-box 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPD52L1 tumor protein D52-like 1
TSPAN1 tetraspanin 1
WBP5 WW domain binding protein 5
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ANXA3 annexin A3
AQP3 aquaporin 3 (Gill blood group)
ARG1 arginase 1
ARHGAP29 Rho GTPase activating protein 29
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASRGL1 asparaginase like 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BACE2 beta-site APP-cleaving enzyme 2
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD93 CD93 molecule
CDC42 cell division cycle 42
CLEC5A C-type lectin domain family 5, member A
CTBP2 C-terminal binding protein 2
CTSG cathepsin G
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DCLK1 doublecortin-like kinase 1
DPT dermatopontin
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EFNB2 ephrin-B2
FOSL1 FOS-like antigen 1
H1F0 H1 histone family, member 0
HAL histidine ammonia-lyase
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INPP1 inositol polyphosphate-1-phosphatase
JAG1 jagged 1
KLF6 Kruppel-like factor 6
KRT23 keratin 23, type I
LAPTM4B lysosomal protein transmembrane 4 beta
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MX1 MX dynamin-like GTPase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NFIB nuclear factor I/B
NGRN neugrin, neurite outgrowth associated
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PMP22 peripheral myelin protein 22
PUF60 poly-U binding splicing factor 60KDa
S100A12 S100 calcium binding protein A12
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SOX4 SRY (sex determining region Y)-box 4
SPTBN1 spectrin, beta, non-erythrocytic 1
TFPI2 tissue factor pathway inhibitor 2
THBD thrombomodulin
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
VCAN versican