BRD-K57011718_UK 356618_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K57011718_UK 356618_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLIC4 chloride intracellular channel 4
COL3A1 collagen, type III, alpha 1
CRABP2 cellular retinoic acid binding protein 2
DDIT4 DNA-damage-inducible transcript 4
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
GPER1 G protein-coupled estrogen receptor 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GUSBP11 glucuronidase, beta pseudogene 11
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
KRT17 keratin 17, type I
KRT5 keratin 5, type II
LGALS1 lectin, galactoside-binding, soluble, 1
LITAF lipopolysaccharide-induced TNF factor
LYZ lysozyme
MBOAT7 membrane bound O-acyltransferase domain containing 7
MYOF myoferlin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PALLD palladin, cytoskeletal associated protein
PRAME preferentially expressed antigen in melanoma
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STC2 stanniocalcin 2
TACSTD2 tumor-associated calcium signal transducer 2
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CHRDL1 chordin-like 1
DHCR24 24-dehydrocholesterol reductase
FDPS farnesyl diphosphate synthase
FOLR1 folate receptor 1 (adult)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
MSLN mesothelin
MSMO1 methylsterol monooxygenase 1
PAIP1 poly(A) binding protein interacting protein 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SQLE squalene epoxidase
SYBU syntabulin (syntaxin-interacting)