BRD-K56658166_N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamide_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K56658166_N-[2-(1H-benzimidazol-2-yl)ethyl]-2-(2-bromophenoxy)acetamide_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AURKB aurora kinase B
BEX4 brain expressed, X-linked 4
BMP2 bone morphogenetic protein 2
BTG3 BTG family, member 3
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CISD1 CDGSH iron sulfur domain 1
CORO1A coronin, actin binding protein, 1A
CPE carboxypeptidase E
CXCL10 chemokine (C-X-C motif) ligand 10
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGKV1-5 immunoglobulin kappa variable 1-5
MMP10 matrix metallopeptidase 10
MMP2 matrix metallopeptidase 2
MUC16 mucin 16, cell surface associated
PLVAP plasmalemma vesicle associated protein
SCGB1D2 secretoglobin, family 1D, member 2
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

decreased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANKRD10 ankyrin repeat domain 10
BASP1 brain abundant, membrane attached signal protein 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DST dystonin
DUSP10 dual specificity phosphatase 10
GCLC glutamate-cysteine ligase, catalytic subunit
HSPB8 heat shock 22kDa protein 8
KYNU kynureninase
LEPR leptin receptor
METTL7A methyltransferase like 7A
MYBPC1 myosin binding protein C, slow type
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NQO1 NAD(P)H dehydrogenase, quinone 1
OSR2 odd-skipped related transciption factor 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PSD3 pleckstrin and Sec7 domain containing 3
RTN2 reticulon 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TPM1 tropomyosin 1 (alpha)
TRIM16 tripartite motif containing 16
VGLL4 vestigial-like family member 4
WNT5A wingless-type MMTV integration site family, member 5A
ZBTB18 zinc finger and BTB domain containing 18