BRD-K55187425_ON-01910_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K55187425_ON-01910_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
APOD apolipoprotein D
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
AURKA aurora kinase A
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
COCH cochlin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYSL2 dihydropyrimidinase-like 2
FHL1 four and a half LIM domains 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOSL1 FOS-like antigen 1
GIMAP6 GTPase, IMAP family member 6
HDGFRP3 hepatoma-derived growth factor, related protein 3
HSPA2 heat shock 70kDa protein 2
IER5 immediate early response 5
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIF14 kinesin family member 14
LAMC2 laminin, gamma 2
MAGEA3 melanoma antigen family A3
MAN1A1 mannosidase, alpha, class 1A, member 1
MICB MHC class I polypeptide-related sequence B
OSR2 odd-skipped related transciption factor 2
PHYH phytanoyl-CoA 2-hydroxylase
PRKCH protein kinase C, eta
RBP4 retinol binding protein 4, plasma
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL37A ribosomal protein L37a
SDC2 syndecan 2
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
TMSB15A thymosin beta 15a
TPM1 tropomyosin 1 (alpha)
TTN titin
TXNL4B thioredoxin-like 4B

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCL6 B-cell CLL/lymphoma 6
BEX1 brain expressed, X-linked 1
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
CFB complement factor B
CYB5A cytochrome b5 type A (microsomal)
DDIT4 DNA-damage-inducible transcript 4
ECHDC2 enoyl CoA hydratase domain containing 2
EFS embryonal Fyn-associated substrate
FAM63A family with sequence similarity 63, member A
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FLRT2 fibronectin leucine rich transmembrane protein 2
GDF15 growth differentiation factor 15
GPX1 glutathione peroxidase 1
GRB14 growth factor receptor-bound protein 14
HIST1H4C histone cluster 1, H4c
IFITM1 interferon induced transmembrane protein 1
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KAZN kazrin, periplakin interacting protein
KCTD12 potassium channel tetramerization domain containing 12
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LTBP3 latent transforming growth factor beta binding protein 3
LYZ lysozyme
METTL7A methyltransferase like 7A
MTCL1 microtubule crosslinking factor 1
PDZK1IP1 PDZK1 interacting protein 1
PLAT plasminogen activator, tissue
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
TOM1L1 target of myb1 (chicken)-like 1
XIST X inactive specific transcript (non-protein coding)