BRD-K54997624_BYL719_MCF10A_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K54997624_BYL719_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ADGRG6 adhesion G protein-coupled receptor G6
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BTG1 B-cell translocation gene 1, anti-proliferative
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHIC2 cysteine-rich hydrophobic domain 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DPYSL2 dihydropyrimidinase-like 2
DUSP1 dual specificity phosphatase 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GRK5 G protein-coupled receptor kinase 5
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
KDM5D lysine (K)-specific demethylase 5D
KYNU kynureninase
MAOA monoamine oxidase A
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PHKB phosphorylase kinase, beta
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPS4Y1 ribosomal protein S4, Y-linked 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC22D3 TSC22 domain family, member 3
USP6NL USP6 N-terminal like

decreased expression

Symbol Name
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADM adrenomedullin
ADO 2-aminoethanethiol (cysteamine) dioxygenase
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BEX1 brain expressed, X-linked 1
BHLHE41 basic helix-loop-helix family, member e41
C3 complement component 3
CBFB core-binding factor, beta subunit
CCND1 cyclin D1
COL5A2 collagen, type V, alpha 2
CPVL carboxypeptidase, vitellogenic-like
CXCL14 chemokine (C-X-C motif) ligand 14
EGR2 early growth response 2
EPHA3 EPH receptor A3
JUN jun proto-oncogene
KRT17 keratin 17, type I
LMO3 LIM domain only 3 (rhombotin-like 2)
NOSIP nitric oxide synthase interacting protein
PLBD1 phospholipase B domain containing 1
PPIF peptidylprolyl isomerase F
PRMT1 protein arginine methyltransferase 1
RPIA ribose 5-phosphate isomerase A
SDC4 syndecan 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SOX9 SRY (sex determining region Y)-box 9
SPAG4 sperm associated antigen 4
TF transferrin
TNC tenascin C
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TUBB2A tubulin, beta 2A class IIa