BRD-K54997624_BYL719_BT20_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-K54997624_BYL719_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AQP3 aquaporin 3 (Gill blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL6 B-cell CLL/lymphoma 6
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
CCDC28A coiled-coil domain containing 28A
CD52 CD52 molecule
CDK19 cyclin-dependent kinase 19
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC2B C-type lectin domain family 2, member B
CXADR coxsackie virus and adenovirus receptor
CYTH1 cytohesin 1
DAPK1 death-associated protein kinase 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
ERBB3 erb-b2 receptor tyrosine kinase 3
F11R F11 receptor
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXO4 forkhead box O4
FST follistatin
FZD7 frizzled class receptor 7
GJA1 gap junction protein, alpha 1, 43kDa
GLUL glutamate-ammonia ligase
GRB10 growth factor receptor-bound protein 10
H2BFS H2B histone family, member S (pseudogene)
HECA headcase homolog (Drosophila)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IFNGR1 interferon gamma receptor 1
IRS2 insulin receptor substrate 2
KIAA1033 KIAA1033
KLHDC2 kelch domain containing 2
KLHL24 kelch-like family member 24
KRAS Kirsten rat sarcoma viral oncogene homolog
LBH limb bud and heart development
LGALS8 lectin, galactoside-binding, soluble, 8
LUC7L3 LUC7-like 3 (S. cerevisiae)
MAN1A1 mannosidase, alpha, class 1A, member 1
MSMB microseminoprotein, beta-
MT1F metallothionein 1F
MT1G metallothionein 1G
MXI1 MAX interactor 1, dimerization protein
OPN3 opsin 3
OXTR oxytocin receptor
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLIN2 perilipin 2
RAB31 RAB31, member RAS oncogene family
RBM47 RNA binding motif protein 47
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS1 regulator of G-protein signaling 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SERINC5 serine incorporator 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGRL SH3 domain binding glutamate-rich protein like
STON1 stonin 1
TCF4 transcription factor 4
TGIF1 TGFB-induced factor homeobox 1
TNS1 tensin 1
TSC22D3 TSC22 domain family, member 3
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CD24 CD24 molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
COPS6 COP9 signalosome subunit 6
CSE1L CSE1 chromosome segregation 1-like (yeast)
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FLRT3 fibronectin leucine rich transmembrane protein 3
G0S2 G0/G1 switch 2
GINS2 GINS complex subunit 2 (Psf2 homolog)
HOXB6 homeobox B6
HOXC10 homeobox C10
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCTD12 potassium channel tetramerization domain containing 12
LIPG lipase, endothelial
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM6 minichromosome maintenance complex component 6
MMP12 matrix metallopeptidase 12
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOLC1 nucleolar and coiled-body phosphoprotein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PARP1 poly (ADP-ribose) polymerase 1
PFN2 profilin 2
PNP purine nucleoside phosphorylase
PPIF peptidylprolyl isomerase F
PRDX2 peroxiredoxin 2
RRM2 ribonucleotide reductase M2
S100A6 S100 calcium binding protein A6
S100A9 S100 calcium binding protein A9
SET SET nuclear proto-oncogene
SLC2A4RG SLC2A4 regulator
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TLR4 toll-like receptor 4
TYMS thymidylate synthetase
UBE2E3 ubiquitin-conjugating enzyme E2E 3