BRD-K54256913_MK-1775_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

16 genes differentially expressed following the BRD-K54256913_MK-1775_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMOTL2 angiomotin like 2
ATF3 activating transcription factor 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
GADD45A growth arrest and DNA-damage-inducible, alpha
GPX3 glutathione peroxidase 3
IER5 immediate early response 5
KRT23 keratin 23, type I
PHLDA2 pleckstrin homology-like domain, family A, member 2
PPAP2B phosphatidic acid phosphatase type 2B
TACSTD2 tumor-associated calcium signal transducer 2
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CDC25A cell division cycle 25A
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
SNAP25 synaptosomal-associated protein, 25kDa