BRD-K53566850_1-(4-chlorobenzyl)-4-[4-(2-methylphenyl)-1-piperazinyl]-1H-pyrazolo[3,4-d]pyrimidine_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

61 genes differentially expressed following the BRD-K53566850_1-(4-chlorobenzyl)-4-[4-(2-methylphenyl)-1-piperazinyl]-1H-pyrazolo[3,4-d]pyrimidine_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA2 acetyl-CoA acyltransferase 2
ANGPTL2 angiopoietin-like 2
ATF3 activating transcription factor 3
BZW2 basic leucine zipper and W2 domains 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL11A1 collagen, type XI, alpha 1
COL5A1 collagen, type V, alpha 1
COMP cartilage oligomeric matrix protein
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
GAS1 growth arrest-specific 1
GATA6 GATA binding protein 6
GSTM3 glutathione S-transferase mu 3 (brain)
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KLF2 Kruppel-like factor 2
LMCD1 LIM and cysteine-rich domains 1
MAMLD1 mastermind-like domain containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
NMU neuromedin U
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDLIM3 PDZ and LIM domain 3
PEG10 paternally expressed 10
PLAT plasminogen activator, tissue
PLCB4 phospholipase C, beta 4
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
RGS2 regulator of G-protein signaling 2
RRAGD Ras-related GTP binding D
S100A14 S100 calcium binding protein A14
SCYL3 SCY1-like 3 (S. cerevisiae)
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SOX9 SRY (sex determining region Y)-box 9
TESK1 testis-specific kinase 1
THBS1 thrombospondin 1
TUBA1A tubulin, alpha 1a

decreased expression

Symbol Name
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
C2CD2 C2 calcium-dependent domain containing 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCLK1 doublecortin-like kinase 1
GAL galanin/GMAP prepropeptide
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
MX1 MX dynamin-like GTPase 1
NEFH neurofilament, heavy polypeptide
NEFL neurofilament, light polypeptide
P3H2 prolyl 3-hydroxylase 2
PIEZO2 piezo-type mechanosensitive ion channel component 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNASET2 ribonuclease T2
RPL38 ribosomal protein L38
RUNX3 runt-related transcription factor 3
SEPP1 selenoprotein P, plasma, 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SYBU syntabulin (syntaxin-interacting)
TBX3 T-box 3
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
ZNF589 zinc finger protein 589