BRD-K53414658_tivozanib_A549_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-K53414658_tivozanib_A549_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
BEX1 brain expressed, X-linked 1
C1QB complement component 1, q subcomponent, B chain
CA2 carbonic anhydrase II
CES1 carboxylesterase 1
CRYAB crystallin, alpha B
FAM63A family with sequence similarity 63, member A
FCGBP Fc fragment of IgG binding protein
GADD45B growth arrest and DNA-damage-inducible, beta
GPX3 glutathione peroxidase 3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOOK2 hook microtubule-tethering protein 2
IGLV2-23 immunoglobulin lambda variable 2-23
NXN nucleoredoxin

decreased expression

Symbol Name
ANXA1 annexin A1
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
HBB hemoglobin, beta
HOXC6 homeobox C6
KYNU kynureninase
S100P S100 calcium binding protein P