BRD-K52911425_GDC-0941_HS578T_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-K52911425_GDC-0941_HS578T_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
ADRB2 adrenoceptor beta 2, surface
AREG amphiregulin
ARG1 arginase 1
ASPN asporin
ASXL2 additional sex combs like transcriptional regulator 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C7 complement component 7
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD36 CD36 molecule (thrombospondin receptor)
CDC25B cell division cycle 25B
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CFB complement factor B
COL10A1 collagen, type X, alpha 1
COLEC11 collectin sub-family member 11
CREB1 cAMP responsive element binding protein 1
CST1 cystatin SN
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DLK1 delta-like 1 homolog (Drosophila)
EGR1 early growth response 1
EGR3 early growth response 3
F13A1 coagulation factor XIII, A1 polypeptide
FABP4 fatty acid binding protein 4, adipocyte
FAXDC2 fatty acid hydroxylase domain containing 2
FGFR2 fibroblast growth factor receptor 2
FOXO4 forkhead box O4
FXYD3 FXYD domain containing ion transport regulator 3
GAGE3 G antigen 3
GATA3 GATA binding protein 3
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPX3 glutathione peroxidase 3
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IRS1 insulin receptor substrate 1
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KDM7A lysine (K)-specific demethylase 7A
KLF10 Kruppel-like factor 10
LDB2 LIM domain binding 2
LDLR low density lipoprotein receptor
LOC100272216 uncharacterized LOC100272216
LY75 lymphocyte antigen 75
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAN1A1 mannosidase, alpha, class 1A, member 1
MTSS1 metastasis suppressor 1
N4BP2L1 NEDD4 binding protein 2-like 1
NOS3 nitric oxide synthase 3 (endothelial cell)
OSBPL3 oxysterol binding protein-like 3
PDE2A phosphodiesterase 2A, cGMP-stimulated
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PROM1 prominin 1
RAB25 RAB25, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS2 thrombospondin 2
TRBC1 T cell receptor beta constant 1
TRIB2 tribbles pseudokinase 2
TRPS1 trichorhinophalangeal syndrome I
TSPAN5 tetraspanin 5
TSPAN7 tetraspanin 7
VCAN versican
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
BASP1 brain abundant, membrane attached signal protein 1
CDC42 cell division cycle 42
CDC6 cell division cycle 6
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSRP1 cysteine and glycine-rich protein 1
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ENO1 enolase 1, (alpha)
FEN1 flap structure-specific endonuclease 1
LAPTM4B lysosomal protein transmembrane 4 beta
LITAF lipopolysaccharide-induced TNF factor
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NME1 NME/NM23 nucleoside diphosphate kinase 1
PCNA proliferating cell nuclear antigen
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
RFC2 replication factor C (activator 1) 2, 40kDa
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TPM2 tropomyosin 2 (beta)
TYMS thymidylate synthetase
ZDHHC6 zinc finger, DHHC-type containing 6
ZIC1 Zic family member 1