BRD-K52911425_-666_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K52911425_-666_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CXADR coxsackie virus and adenovirus receptor
DOCK9 dedicator of cytokinesis 9
DSP desmoplakin
HBP1 HMG-box transcription factor 1
HMOX1 heme oxygenase 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP7 microtubule-associated protein 7
MTUS1 microtubule associated tumor suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUPR1 nuclear protein, transcriptional regulator, 1
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PERP PERP, TP53 apoptosis effector
PLXND1 plexin D1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC38A2 solute carrier family 38, member 2
TARP TCR gamma alternate reading frame protein
TM4SF1 transmembrane 4 L six family member 1
TPP1 tripeptidyl peptidase I
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
BAG2 BCL2-associated athanogene 2
BST2 bone marrow stromal cell antigen 2
CDC25A cell division cycle 25A
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EFNB2 ephrin-B2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF5 eukaryotic translation initiation factor 5
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
FAM63A family with sequence similarity 63, member A
FOSL1 FOS-like antigen 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPH1 heat shock 105kDa/110kDa protein 1
JMJD6 jumonji domain containing 6
LGALS1 lectin, galactoside-binding, soluble, 1
NOP16 NOP16 nucleolar protein
NQO1 NAD(P)H dehydrogenase, quinone 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRPF4 pre-mRNA processing factor 4
PRR7 proline rich 7 (synaptic)
PSD3 pleckstrin and Sec7 domain containing 3
RGS2 regulator of G-protein signaling 2
RHOBTB3 Rho-related BTB domain containing 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TUBB2A tubulin, beta 2A class IIa