BRD-K51816706_Oxindole I_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K51816706_Oxindole I_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ARG2 arginase 2
ARMCX1 armadillo repeat containing, X-linked 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP11B ATPase, class VI, type 11B
CA2 carbonic anhydrase II
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD40 CD40 molecule, TNF receptor superfamily member 5
CFB complement factor B
CHGB chromogranin B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CPB1 carboxypeptidase B1 (tissue)
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CTNND1 catenin (cadherin-associated protein), delta 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FGL2 fibrinogen-like 2
FHL1 four and a half LIM domains 1
GJA1 gap junction protein, alpha 1, 43kDa
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
KCNK3 potassium channel, two pore domain subfamily K, member 3
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT19 keratin 19, type I
KRT5 keratin 5, type II
MAGEA3 melanoma antigen family A3
MFAP5 microfibrillar associated protein 5
MSMB microseminoprotein, beta-
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NMU neuromedin U
NPTX2 neuronal pentraxin II
NT5DC2 5'-nucleotidase domain containing 2
OLFM4 olfactomedin 4
P3H2 prolyl 3-hydroxylase 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCP4 Purkinje cell protein 4
PDZK1IP1 PDZK1 interacting protein 1
PLAGL1 pleiomorphic adenoma gene-like 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRDX2 peroxiredoxin 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGCC regulator of cell cycle
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SDC1 syndecan 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLPI secretory leukocyte peptidase inhibitor
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TSPAN12 tetraspanin 12
VEGFA vascular endothelial growth factor A
VSNL1 visinin-like 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
CBR3 carbonyl reductase 3
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHL1 cell adhesion molecule L1-like
CRIP1 cysteine-rich protein 1 (intestinal)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYTL1 cytokine-like 1
DLC1 DLC1 Rho GTPase activating protein
ECI2 enoyl-CoA delta isomerase 2
EGR3 early growth response 3
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FOLR1 folate receptor 1 (adult)
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ITM2A integral membrane protein 2A
NAV2 neuron navigator 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIB nuclear factor I/B
NOTCH2NL notch 2 N-terminal like
PRKCA protein kinase C, alpha
PTGES prostaglandin E synthase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RCAN1 regulator of calcineurin 1
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STOM stomatin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNC tenascin C
TSPAN8 tetraspanin 8
ZBTB18 zinc finger and BTB domain containing 18