BRD-K51781482_IKK-3 Inhibitor IX_HA1E_6.0_h_6.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K51781482_IKK-3 Inhibitor IX_HA1E_6.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BHLHE40 basic helix-loop-helix family, member e40
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CKAP4 cytoskeleton-associated protein 4
DUSP14 dual specificity phosphatase 14
FOSL1 FOS-like antigen 1
IER3 immediate early response 3
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MYC v-myc avian myelocytomatosis viral oncogene homolog
S100A2 S100 calcium binding protein A2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
TGFBR3 transforming growth factor, beta receptor III
UGCG UDP-glucose ceramide glucosyltransferase
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ALDOB aldolase B, fructose-bisphosphate
ANGPTL2 angiopoietin-like 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CAST calpastatin
CCNE2 cyclin E2
ECM1 extracellular matrix protein 1
GREM1 gremlin 1, DAN family BMP antagonist
MME membrane metallo-endopeptidase
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
S100P S100 calcium binding protein P
SPINK1 serine peptidase inhibitor, Kazal type 1