BRD-K51751936_Alfadolone acetate_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K51751936_Alfadolone acetate_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
DUSP10 dual specificity phosphatase 10
EPCAM epithelial cell adhesion molecule
EPS8 epidermal growth factor receptor pathway substrate 8
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOLR1 folate receptor 1 (adult)
FUCA1 fucosidase, alpha-L- 1, tissue
FYB FYN binding protein
IGFBP4 insulin-like growth factor binding protein 4
IGLJ3 immunoglobulin lambda joining 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
LTF lactotransferrin
MT1E metallothionein 1E
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MYH11 myosin, heavy chain 11, smooth muscle
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PTGES prostaglandin E synthase
SPTBN1 spectrin, beta, non-erythrocytic 1
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ALAS1 5'-aminolevulinate synthase 1
ALB albumin
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASPN asporin
BEX1 brain expressed, X-linked 1
C14ORF132 chromosome 14 open reading frame 132
CA2 carbonic anhydrase II
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CD40 CD40 molecule, TNF receptor superfamily member 5
COL3A1 collagen, type III, alpha 1
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CREB1 cAMP responsive element binding protein 1
CXCL10 chemokine (C-X-C motif) ligand 10
DENND1B DENN/MADD domain containing 1B
DPYSL3 dihydropyrimidinase-like 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
GAL galanin/GMAP prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GSTM3 glutathione S-transferase mu 3 (brain)
HBB hemoglobin, beta
IL32 interleukin 32
KIF1A kinesin family member 1A
KLHL41 kelch-like family member 41
KRT23 keratin 23, type I
LUM lumican
MB myoglobin
MFAP2 microfibrillar-associated protein 2
MMP2 matrix metallopeptidase 2
NEB nebulin
PAPD7 PAP associated domain containing 7
PBX3 pre-B-cell leukemia homeobox 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
RTN2 reticulon 2
SCGB1D2 secretoglobin, family 1D, member 2
SEPP1 selenoprotein P, plasma, 1
SEPT10 septin 10
SLN sarcolipin
SNX7 sorting nexin 7
SST somatostatin
SULF1 sulfatase 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
THBS2 thrombospondin 2
THY1 Thy-1 cell surface antigen
TNNC1 troponin C type 1 (slow)
TNNT1 troponin T type 1 (skeletal, slow)
TPBG trophoblast glycoprotein
TTN titin
TUBB2B tubulin, beta 2B class IIb
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)