BRD-K51575138_TPCA-1_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

19 genes differentially expressed following the BRD-K51575138_TPCA-1_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CTSH cathepsin H
HOMER3 homer scaffolding protein 3
MEIS2 Meis homeobox 2
PEG3 paternally expressed 3
SPINT2 serine peptidase inhibitor, Kunitz type, 2

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
CDK6 cyclin-dependent kinase 6
COL3A1 collagen, type III, alpha 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
GPM6B glycoprotein M6B
KRT14 keratin 14, type I
PI3 peptidase inhibitor 3, skin-derived
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
RUNX3 runt-related transcription factor 3
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
ZNF185 zinc finger protein 185 (LIM domain)