BRD-K50387473_XMD-892_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K50387473_XMD-892_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
ASMTL acetylserotonin O-methyltransferase-like
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BEX1 brain expressed, X-linked 1
CA12 carbonic anhydrase XII
CCL2 chemokine (C-C motif) ligand 2
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
EID1 EP300 interacting inhibitor of differentiation 1
EMP1 epithelial membrane protein 1
GNB5 guanine nucleotide binding protein (G protein), beta 5
HEATR1 HEAT repeat containing 1
HIST1H1C histone cluster 1, H1c
HP haptoglobin
IER5 immediate early response 5
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP1 latent transforming growth factor beta binding protein 1
NGRN neugrin, neurite outgrowth associated
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRAF2 PRA1 domain family, member 2
PYCARD PYD and CARD domain containing
RPS4Y1 ribosomal protein S4, Y-linked 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SYK spleen tyrosine kinase
TFF3 trefoil factor 3 (intestinal)

decreased expression

Symbol Name
ANGPT1 angiopoietin 1
APOL1 apolipoprotein L, 1
AQP3 aquaporin 3 (Gill blood group)
C6ORF62 chromosome 6 open reading frame 62
CADM1 cell adhesion molecule 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFB complement factor B
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
COCH cochlin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
EGFL6 EGF-like-domain, multiple 6
EGFR epidermal growth factor receptor
EIF5 eukaryotic translation initiation factor 5
ENO1 enolase 1, (alpha)
FAM129A family with sequence similarity 129, member A
FOSL1 FOS-like antigen 1
FZD5 frizzled class receptor 5
GCH1 GTP cyclohydrolase 1
GNAS GNAS complex locus
HOPX HOP homeobox
IFRD2 interferon-related developmental regulator 2
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
KAZN kazrin, periplakin interacting protein
KIF14 kinesin family member 14
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
NR2F6 nuclear receptor subfamily 2, group F, member 6
P3H2 prolyl 3-hydroxylase 2
PAM peptidylglycine alpha-amidating monooxygenase
PAX6 paired box 6
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1
POSTN periostin, osteoblast specific factor
PPIF peptidylprolyl isomerase F
PYCR1 pyrroline-5-carboxylate reductase 1
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TAGLN2 transgelin 2
TM4SF1 transmembrane 4 L six family member 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TREM1 triggering receptor expressed on myeloid cells 1
TSPAN4 tetraspanin 4
VCAN versican
VEGFA vascular endothelial growth factor A
ZNF91 zinc finger protein 91