BRD-K50387473_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

128 genes differentially expressed following the BRD-K50387473_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
BASP1 brain abundant, membrane attached signal protein 1
BRD2 bromodomain containing 2
CA1 carbonic anhydrase I
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CANX calnexin
CCNL1 cyclin L1
CD81 CD81 molecule
CES1 carboxylesterase 1
CHGB chromogranin B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CREG1 cellular repressor of E1A-stimulated genes 1
CTR9 CTR9, Paf1/RNA polymerase II complex component
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
FAM117A family with sequence similarity 117, member A
FBXO21 F-box protein 21
FLNA filamin A, alpha
G6PD glucose-6-phosphate dehydrogenase
GALC galactosylceramidase
GRN granulin
GSDMB gasdermin B
GULP1 GULP, engulfment adaptor PTB domain containing 1
H2BFS H2B histone family, member S (pseudogene)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHM immunoglobulin heavy constant mu
L1CAM L1 cell adhesion molecule
LEPR leptin receptor
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MPDZ multiple PDZ domain protein
MYO1B myosin IB
OPN3 opsin 3
PALLD palladin, cytoskeletal associated protein
PKP2 plakophilin 2
RAB4A RAB4A, member RAS oncogene family
RBBP6 retinoblastoma binding protein 6
RNF167 ring finger protein 167
SAT1 spermidine/spermine N1-acetyltransferase 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SCPEP1 serine carboxypeptidase 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
STX1A syntaxin 1A (brain)
TGM2 transglutaminase 2
TMED2 transmembrane emp24 domain trafficking protein 2
TRIB2 tribbles pseudokinase 2
TUBA1A tubulin, alpha 1a
TUBA4A tubulin, alpha 4a
TXNIP thioredoxin interacting protein
UBE2S ubiquitin-conjugating enzyme E2S
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VIM vimentin
YBX1 Y box binding protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AFP alpha-fetoprotein
ANXA7 annexin A7
ATF3 activating transcription factor 3
CALB1 calbindin 1, 28kDa
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLDN4 claudin 4
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL3 chemokine (C-X-C motif) ligand 3
DRAM1 DNA-damage regulated autophagy modulator 1
DUSP22 dual specificity phosphatase 22
ECM1 extracellular matrix protein 1
EMG1 EMG1 N1-specific pseudouridine methyltransferase
EMP1 epithelial membrane protein 1
EVI2A ecotropic viral integration site 2A
F5 coagulation factor V (proaccelerin, labile factor)
FGFR3 fibroblast growth factor receptor 3
FHL2 four and a half LIM domains 2
GBP1 guanylate binding protein 1, interferon-inducible
GLTP glycolipid transfer protein
GPR171 G protein-coupled receptor 171
GPRC5A G protein-coupled receptor, class C, group 5, member A
HDDC2 HD domain containing 2
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
ICAM2 intercellular adhesion molecule 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL1R2 interleukin 1 receptor, type II
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KRT23 keratin 23, type I
LMO3 LIM domain only 3 (rhombotin-like 2)
LOX lysyl oxidase
LRRC15 leucine rich repeat containing 15
LYZ lysozyme
MSLN mesothelin
NUPR1 nuclear protein, transcriptional regulator, 1
PARP2 poly (ADP-ribose) polymerase 2
PCP4 Purkinje cell protein 4
PDGFA platelet-derived growth factor alpha polypeptide
PDGFC platelet derived growth factor C
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAC8 placenta-specific 8
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PSCA prostate stem cell antigen
PSPH phosphoserine phosphatase
RAB15 RAB15, member RAS oncogene family
RHOBTB3 Rho-related BTB domain containing 3
S100P S100 calcium binding protein P
SCEL sciellin
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SORBS3 sorbin and SH3 domain containing 3
SORD sorbitol dehydrogenase
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRR1A small proline-rich protein 1A
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TF transferrin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
ZMAT3 zinc finger, matrin-type 3