BRD-K49669041_BX-912_SKBR3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

92 genes differentially expressed following the BRD-K49669041_BX-912_SKBR3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
BASP1 brain abundant, membrane attached signal protein 1
CST3 cystatin C
CXCR4 chemokine (C-X-C motif) receptor 4
DAXX death-domain associated protein
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FN1 fibronectin 1
GPD1L glycerol-3-phosphate dehydrogenase 1-like
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP7 insulin-like growth factor binding protein 7
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0753 KIAA0753
LGALS1 lectin, galactoside-binding, soluble, 1
LOC100505650 uncharacterized LOC100505650
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MSLN mesothelin
MXRA7 matrix-remodelling associated 7
MYH10 myosin, heavy chain 10, non-muscle
NOTCH2NL notch 2 N-terminal like
PFKP phosphofructokinase, platelet
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PYGL phosphorylase, glycogen, liver
SCGB2A1 secretoglobin, family 2A, member 1
SESN1 sestrin 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TSPAN8 tetraspanin 8
VIM vimentin
ZNF365 zinc finger protein 365

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADGRF5 adhesion G protein-coupled receptor F5
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALOX5 arachidonate 5-lipoxygenase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
C3ORF14 chromosome 3 open reading frame 14
CALML4 calmodulin-like 4
CAPN1 calpain 1, (mu/I) large subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CPA3 carboxypeptidase A3 (mast cell)
CPM carboxypeptidase M
CTGF connective tissue growth factor
CXCL14 chemokine (C-X-C motif) ligand 14
EPHA3 EPH receptor A3
HOXC10 homeobox C10
HOXD1 homeobox D1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPB1 heat shock 27kDa protein 1
IFITM1 interferon induced transmembrane protein 1
IGFBP5 insulin-like growth factor binding protein 5
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
JADE2 jade family PHD finger 2
KLF10 Kruppel-like factor 10
LMO3 LIM domain only 3 (rhombotin-like 2)
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MMP3 matrix metallopeptidase 3
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NEFH neurofilament, heavy polypeptide
NELL2 NEL-like 2 (chicken)
NTS neurotensin
PELI1 pellino E3 ubiquitin protein ligase 1
PLAC8 placenta-specific 8
PPAP2B phosphatidic acid phosphatase type 2B
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RGCC regulator of cell cycle
RHOB ras homolog family member B
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SEPW1 selenoprotein W, 1
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TXNIP thioredoxin interacting protein