BRD-K49669041_BX-912_MDAMB231_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K49669041_BX-912_MDAMB231_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AEBP1 AE binding protein 1
AGR2 anterior gradient 2
CIB1 calcium and integrin binding 1 (calmyrin)
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
CRELD2 cysteine-rich with EGF-like domains 2
CXCL12 chemokine (C-X-C motif) ligand 12
DDIT4 DNA-damage-inducible transcript 4
EIF5A eukaryotic translation initiation factor 5A
ERBB2 erb-b2 receptor tyrosine kinase 2
FBLN1 fibulin 1
FN1 fibronectin 1
GSTA1 glutathione S-transferase alpha 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LXN latexin
MLPH melanophilin
NES nestin
NR4A3 nuclear receptor subfamily 4, group A, member 3
PHGDH phosphoglycerate dehydrogenase
POSTN periostin, osteoblast specific factor
PPIB peptidylprolyl isomerase B (cyclophilin B)
PYCARD PYD and CARD domain containing
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPL37A ribosomal protein L37a
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SELENBP1 selenium binding protein 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SGK1 serum/glucocorticoid regulated kinase 1
STC1 stanniocalcin 1
TAGLN transgelin
TFF3 trefoil factor 3 (intestinal)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THAP11 THAP domain containing 11
TSC22D3 TSC22 domain family, member 3
TSPAN8 tetraspanin 8
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
APLP2 amyloid beta (A4) precursor-like protein 2
CADM1 cell adhesion molecule 1
CD9 CD9 molecule
CPM carboxypeptidase M
CTBP1 C-terminal binding protein 1
DFNA5 deafness, autosomal dominant 5
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EHD3 EH-domain containing 3
EMX2 empty spiracles homeobox 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
GLRB glycine receptor, beta
GRIA2 glutamate receptor, ionotropic, AMPA 2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KDM5D lysine (K)-specific demethylase 5D
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
MSLN mesothelin
NMU neuromedin U
OXTR oxytocin receptor
PICALM phosphatidylinositol binding clathrin assembly protein
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PNMAL1 paraneoplastic Ma antigen family-like 1
PRPF4 pre-mRNA processing factor 4
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RBBP8 retinoblastoma binding protein 8
RBM34 RNA binding motif protein 34