BRD-K49669041_BX-912_MDAMB231_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K49669041_BX-912_MDAMB231_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ADGRG6 adhesion G protein-coupled receptor G6
AHNAK AHNAK nucleoprotein
BMP6 bone morphogenetic protein 6
C6ORF62 chromosome 6 open reading frame 62
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLIC4 chloride intracellular channel 4
DAPK1 death-associated protein kinase 1
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPCAM epithelial cell adhesion molecule
F11R F11 receptor
FGFR1 fibroblast growth factor receptor 1
GPNMB glycoprotein (transmembrane) nmb
HBB hemoglobin, beta
IL1R2 interleukin 1 receptor, type II
JAG1 jagged 1
KRT14 keratin 14, type I
KRT5 keratin 5, type II
MGLL monoglyceride lipase
PECAM1 platelet/endothelial cell adhesion molecule 1
PSAT1 phosphoserine aminotransferase 1
RUNX3 runt-related transcription factor 3
SFN stratifin
SPTBN1 spectrin, beta, non-erythrocytic 1
TCF4 transcription factor 4
TFF1 trefoil factor 1
TSC22D3 TSC22 domain family, member 3
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
AURKB aurora kinase B
GALE UDP-galactose-4-epimerase
GPX3 glutathione peroxidase 3
H2AFX H2A histone family, member X
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HILPDA hypoxia inducible lipid droplet-associated
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
MCM3 minichromosome maintenance complex component 3
NUP85 nucleoporin 85kDa
OXA1L oxidase (cytochrome c) assembly 1-like
PARP2 poly (ADP-ribose) polymerase 2
PLAU plasminogen activator, urokinase
RFC4 replication factor C (activator 1) 4, 37kDa
RRM2 ribonucleotide reductase M2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa