BRD-K49669041_BX-912_MCF7_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

62 genes differentially expressed following the BRD-K49669041_BX-912_MCF7_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMDEC1 ADAM-like, decysin 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CD24 CD24 molecule
CFI complement factor I
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CHPT1 choline phosphotransferase 1
CRABP1 cellular retinoic acid binding protein 1
CTGF connective tissue growth factor
DAAM2 dishevelled associated activator of morphogenesis 2
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
FAM171A1 family with sequence similarity 171, member A1
FGFR2 fibroblast growth factor receptor 2
FNBP1 formin binding protein 1
FOLR1 folate receptor 1 (adult)
FUCA1 fucosidase, alpha-L- 1, tissue
GLRX glutaredoxin (thioltransferase)
GPX3 glutathione peroxidase 3
GREM1 gremlin 1, DAN family BMP antagonist
IER3 immediate early response 3
IGKC immunoglobulin kappa constant
IL1R2 interleukin 1 receptor, type II
ITGB5 integrin, beta 5
JCHAIN joining chain of multimeric IgA and IgM
LRRC16A leucine rich repeat containing 16A
NNMT nicotinamide N-methyltransferase
NUCB2 nucleobindin 2
PYGL phosphorylase, glycogen, liver
RAP1GAP RAP1 GTPase activating protein
SDC4 syndecan 4
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SST somatostatin
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TCEA2 transcription elongation factor A (SII), 2
TNIP1 TNFAIP3 interacting protein 1
TSPAN4 tetraspanin 4
VAMP8 vesicle-associated membrane protein 8

decreased expression

Symbol Name
BRCA1 breast cancer 1, early onset
CCND2 cyclin D2
CDC45 cell division cycle 45
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHGB chromogranin B
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFS embryonal Fyn-associated substrate
GINS2 GINS complex subunit 2 (Psf2 homolog)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFRD2 interferon-related developmental regulator 2
IGFBP5 insulin-like growth factor binding protein 5
JUN jun proto-oncogene
KANK2 KN motif and ankyrin repeat domains 2
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NEFH neurofilament, heavy polypeptide
NID2 nidogen 2 (osteonidogen)
PITX1 paired-like homeodomain 1
PLAGL1 pleiomorphic adenoma gene-like 1
RAD51C RAD51 paralog C
RGS2 regulator of G-protein signaling 2
RPA3 replication protein A3, 14kDa
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa