BRD-K49669041_BX-912_HEPG2_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

70 genes differentially expressed following the BRD-K49669041_BX-912_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
BASP1 brain abundant, membrane attached signal protein 1
CD47 CD47 molecule
CLC Charcot-Leyden crystal galectin
CTSZ cathepsin Z
CXCL14 chemokine (C-X-C motif) ligand 14
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYR61 cysteine-rich, angiogenic inducer, 61
FHL1 four and a half LIM domains 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPRC5A G protein-coupled receptor, class C, group 5, member A
HIST1H2BK histone cluster 1, H2bk
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IDS iduronate 2-sulfatase
INHBB inhibin, beta B
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT81 keratin 81, type II
LOXL1 lysyl oxidase-like 1
MLPH melanophilin
NKX2-1 NK2 homeobox 1
NT5E 5'-nucleotidase, ecto (CD73)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PPARG peroxisome proliferator-activated receptor gamma
S100A4 S100 calcium binding protein A4
SDC4 syndecan 4
SEPW1 selenoprotein W, 1
TRIM2 tripartite motif containing 2
TUBB6 tubulin, beta 6 class V

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CFB complement factor B
CFI complement factor I
CHPT1 choline phosphotransferase 1
COL9A3 collagen, type IX, alpha 3
DSP desmoplakin
ELOVL2 ELOVL fatty acid elongase 2
FGFR3 fibroblast growth factor receptor 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
GSTA4 glutathione S-transferase alpha 4
HP haptoglobin
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
LCN2 lipocalin 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
METTL7A methyltransferase like 7A
MME membrane metallo-endopeptidase
MSX1 msh homeobox 1
MYLK myosin light chain kinase
PEG3 paternally expressed 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PTN pleiotrophin
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
SCRG1 stimulator of chondrogenesis 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SPON1 spondin 1, extracellular matrix protein
TIAM1 T-cell lymphoma invasion and metastasis 1
VDAC1 voltage-dependent anion channel 1