BRD-K49669041_BX-912_BT20_3_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K49669041_BX-912_BT20_3_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AREG amphiregulin
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATF3 activating transcription factor 3
BCL2A1 BCL2-related protein A1
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
CCL20 chemokine (C-C motif) ligand 20
CD163 CD163 molecule
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP2 dual specificity phosphatase 2
EGR1 early growth response 1
EREG epiregulin
FAM171A1 family with sequence similarity 171, member A1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GDF15 growth differentiation factor 15
GSN gelsolin
HCAR3 hydroxycarboxylic acid receptor 3
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
LAPTM5 lysosomal protein transmembrane 5
MGP matrix Gla protein
MMP9 matrix metallopeptidase 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OLFM4 olfactomedin 4
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RGS5 regulator of G-protein signaling 5
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SPP1 secreted phosphoprotein 1
SST somatostatin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOB1 transducer of ERBB2, 1
TSC22D1 TSC22 domain family, member 1
TUBA1A tubulin, alpha 1a

decreased expression

Symbol Name
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CBR3 carbonyl reductase 3
CCNF cyclin F
CD58 CD58 molecule
IGFBP5 insulin-like growth factor binding protein 5
MAN2A1 mannosidase, alpha, class 2A, member 1
NEK7 NIMA-related kinase 7
NRN1 neuritin 1
PLK1 polo-like kinase 1
POPDC3 popeye domain containing 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TCF4 transcription factor 4
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
WNT5A wingless-type MMTV integration site family, member 5A
ZHX2 zinc fingers and homeoboxes 2