BRD-K49669041_BX-912_BT20_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K49669041_BX-912_BT20_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADD3 adducin 3 (gamma)
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASPN asporin
AUTS2 autism susceptibility candidate 2
BGN biglycan
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DCN decorin
DLK1 delta-like 1 homolog (Drosophila)
DPYSL2 dihydropyrimidinase-like 2
FGG fibrinogen gamma chain
FHL1 four and a half LIM domains 1
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPM6B glycoprotein M6B
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
IGFBP4 insulin-like growth factor binding protein 4
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LINC00341 long intergenic non-protein coding RNA 341
LOXL1 lysyl oxidase-like 1
LRRC17 leucine rich repeat containing 17
MFAP2 microfibrillar-associated protein 2
PRUNE prune exopolyphosphatase
PTN pleiotrophin
RAP1GAP RAP1 GTPase activating protein
SATB1 SATB homeobox 1
SELENBP1 selenium binding protein 1
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
THBS2 thrombospondin 2
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ADM adrenomedullin
AIM2 absent in melanoma 2
C10ORF10 chromosome 10 open reading frame 10
CCL5 chemokine (C-C motif) ligand 5
CD8A CD8a molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHGB chromogranin B
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCL13 chemokine (C-X-C motif) ligand 13
CYR61 cysteine-rich, angiogenic inducer, 61
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFA5 defensin, alpha 5, Paneth cell-specific
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM129A family with sequence similarity 129, member A
FAM46A family with sequence similarity 46, member A
FGFR2 fibroblast growth factor receptor 2
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXO3 forkhead box O3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPRC5A G protein-coupled receptor, class C, group 5, member A
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HSPA2 heat shock 70kDa protein 2
JUN jun proto-oncogene
LY75 lymphocyte antigen 75
MME membrane metallo-endopeptidase
NT5E 5'-nucleotidase, ecto (CD73)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
REG3A regenerating islet-derived 3 alpha
RGS1 regulator of G-protein signaling 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SNX10 sorting nexin 10
TBXA2R thromboxane A2 receptor
TMEM255A transmembrane protein 255A
TOR1A torsin family 1, member A (torsin A)
TSPAN5 tetraspanin 5