BRD-K49371609_528116.cdx_NCIH596_6.0_h_0.09_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

118 genes differentially expressed following the BRD-K49371609_528116.cdx_NCIH596_6.0_h_0.09_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT7 acyl-CoA thioesterase 7
ADIRF adipogenesis regulatory factor
AFP alpha-fetoprotein
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALOX15B arachidonate 15-lipoxygenase, type B
ANPEP alanyl (membrane) aminopeptidase
ARID5B AT rich interactive domain 5B (MRF1-like)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
BIRC3 baculoviral IAP repeat containing 3
BMP2 bone morphogenetic protein 2
BTG3 BTG family, member 3
C3 complement component 3
CCL20 chemokine (C-C motif) ligand 20
CD24 CD24 molecule
CD38 CD38 molecule
CD9 CD9 molecule
CNN3 calponin 3, acidic
COL11A1 collagen, type XI, alpha 1
COL6A3 collagen, type VI, alpha 3
CPB1 carboxypeptidase B1 (tissue)
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DLK1 delta-like 1 homolog (Drosophila)
DPP4 dipeptidyl-peptidase 4
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EIF5A eukaryotic translation initiation factor 5A
FBN2 fibrillin 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FST follistatin
GPC3 glypican 3
GSTM3 glutathione S-transferase mu 3 (brain)
HOPX HOP homeobox
IGHM immunoglobulin heavy constant mu
IL1R1 interleukin 1 receptor, type I
KLF6 Kruppel-like factor 6
LAMP3 lysosomal-associated membrane protein 3
LIF leukemia inhibitory factor
LPAR6 lysophosphatidic acid receptor 6
LRRC17 leucine rich repeat containing 17
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NAV3 neuron navigator 3
NEB nebulin
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRIP1 nuclear receptor interacting protein 1
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
NTS neurotensin
OSBPL10 oxysterol binding protein-like 10
P3H2 prolyl 3-hydroxylase 2
PBX3 pre-B-cell leukemia homeobox 3
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGCC regulator of cell cycle
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCRN1 secernin 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC38A1 solute carrier family 38, member 1
SST somatostatin
TIMP3 TIMP metallopeptidase inhibitor 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOX3 TOX high mobility group box family member 3
TPD52 tumor protein D52
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ACTB actin, beta
ADGRG2 adhesion G protein-coupled receptor G2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCNA2 cyclin A2
CDC25B cell division cycle 25B
CSRP1 cysteine and glycine-rich protein 1
CXCL12 chemokine (C-X-C motif) ligand 12
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FEN1 flap structure-specific endonuclease 1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
FZD7 frizzled class receptor 7
GNAS GNAS complex locus
GUSBP3 glucuronidase, beta pseudogene 3
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
JADE1 jade family PHD finger 1
KIAA0485 uncharacterized LOC57235
KIF2C kinesin family member 2C
MARCKS myristoylated alanine-rich protein kinase C substrate
MAT2A methionine adenosyltransferase II, alpha
PDLIM5 PDZ and LIM domain 5
PLCB4 phospholipase C, beta 4
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PROM1 prominin 1
PRPF4 pre-mRNA processing factor 4
RAE1 ribonucleic acid export 1
RFC2 replication factor C (activator 1) 2, 40kDa
RRP1B ribosomal RNA processing 1B
SELL selectin L
TBL1X transducin (beta)-like 1X-linked
THAP11 THAP domain containing 11
TXLNA taxilin alpha
VCAN versican
WIPF2 WAS/WASL interacting protein family, member 2
ZMYM2 zinc finger, MYM-type 2