BRD-K49328571_dasatinib_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K49328571_dasatinib_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C14ORF132 chromosome 14 open reading frame 132
CD44 CD44 molecule (Indian blood group)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CES1 carboxylesterase 1
DAXX death-domain associated protein
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GULP1 GULP, engulfment adaptor PTB domain containing 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HOXC6 homeobox C6
IGFBP7 insulin-like growth factor binding protein 7
MDK midkine (neurite growth-promoting factor 2)
MEIS1 Meis homeobox 1
N4BP2L2 NEDD4 binding protein 2-like 2
PYCARD PYD and CARD domain containing
RGL2 ral guanine nucleotide dissociation stimulator-like 2
SERINC5 serine incorporator 5
SLC35E2B solute carrier family 35, member E2B
SMC1A structural maintenance of chromosomes 1A
SYT1 synaptotagmin I
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
BHLHE41 basic helix-loop-helix family, member e41
CCL2 chemokine (C-C motif) ligand 2
CCNE2 cyclin E2
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CSTA cystatin A (stefin A)
CTSZ cathepsin Z
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EMP1 epithelial membrane protein 1
EREG epiregulin
FCGBP Fc fragment of IgG binding protein
FHL2 four and a half LIM domains 2
GBP1 guanylate binding protein 1, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
HP haptoglobin
IER3 immediate early response 3
JUN jun proto-oncogene
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT14 keratin 14, type I
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PMP22 peripheral myelin protein 22
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SPEN spen family transcriptional repressor
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPM4 tropomyosin 4