BRD-K49055432_A66_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

115 genes differentially expressed following the BRD-K49055432_A66_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALCAM activated leukocyte cell adhesion molecule
AMDHD2 amidohydrolase domain containing 2
ANXA3 annexin A3
AOX1 aldehyde oxidase 1
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ARMCX1 armadillo repeat containing, X-linked 1
BASP1 brain abundant, membrane attached signal protein 1
C10ORF10 chromosome 10 open reading frame 10
CCDC28A coiled-coil domain containing 28A
CCL2 chemokine (C-C motif) ligand 2
CCNG2 cyclin G2
CD36 CD36 molecule (thrombospondin receptor)
CDK14 cyclin-dependent kinase 14
CELF2 CUGBP, Elav-like family member 2
CFD complement factor D (adipsin)
COLEC12 collectin sub-family member 12
CTSG cathepsin G
CXCL12 chemokine (C-X-C motif) ligand 12
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DEGS1 delta(4)-desaturase, sphingolipid 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
ERBB3 erb-b2 receptor tyrosine kinase 3
FABP4 fatty acid binding protein 4, adipocyte
FBN1 fibrillin 1
FBP1 fructose-1,6-bisphosphatase 1
FHL2 four and a half LIM domains 2
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXO4 forkhead box O4
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPNMB glycoprotein (transmembrane) nmb
GSPT2 G1 to S phase transition 2
GSTM3 glutathione S-transferase mu 3 (brain)
HBP1 HMG-box transcription factor 1
HMGB2 high mobility group box 2
HNMT histamine N-methyltransferase
IL1R1 interleukin 1 receptor, type I
KCTD12 potassium channel tetramerization domain containing 12
KLF4 Kruppel-like factor 4 (gut)
MEIS1 Meis homeobox 1
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
NCK2 NCK adaptor protein 2
NEFL neurofilament, light polypeptide
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PBX3 pre-B-cell leukemia homeobox 3
PXDN peroxidasin
RBM47 RNA binding motif protein 47
RFTN1 raftlin, lipid raft linker 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPS4Y1 ribosomal protein S4, Y-linked 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SNN stannin
SORBS3 sorbin and SH3 domain containing 3
SRPX sushi-repeat containing protein, X-linked
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN8 tetraspanin 8
VIM vimentin
YPEL5 yippee-like 5 (Drosophila)
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
BTG3 BTG family, member 3
CCDC86 coiled-coil domain containing 86
CCND2 cyclin D2
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CKB creatine kinase, brain
COL5A2 collagen, type V, alpha 2
EIF5A eukaryotic translation initiation factor 5A
EREG epiregulin
FGFR2 fibroblast growth factor receptor 2
FKBP10 FK506 binding protein 10, 65 kDa
GPI glucose-6-phosphate isomerase
GRIA2 glutamate receptor, ionotropic, AMPA 2
GTF2A2 general transcription factor IIA, 2, 12kDa
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
JMJD6 jumonji domain containing 6
KRT4 keratin 4, type II
LDHB lactate dehydrogenase B
LGALS1 lectin, galactoside-binding, soluble, 1
LMO4 LIM domain only 4
LOC100505650 uncharacterized LOC100505650
LPAR6 lysophosphatidic acid receptor 6
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MMP12 matrix metallopeptidase 12
MSX1 msh homeobox 1
NLRP2 NLR family, pyrin domain containing 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NTS neurotensin
PCDH9 protocadherin 9
PITX1 paired-like homeodomain 1
PLK1 polo-like kinase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POU4F1 POU class 4 homeobox 1
PSAT1 phosphoserine aminotransferase 1
RAB5C RAB5C, member RAS oncogene family
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TARS threonyl-tRNA synthetase
UBE2S ubiquitin-conjugating enzyme E2S
XIST X inactive specific transcript (non-protein coding)