BRD-K48950795_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

62 genes differentially expressed following the BRD-K48950795_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ASXL2 additional sex combs like transcriptional regulator 2
BST2 bone marrow stromal cell antigen 2
CD302 CD302 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES1 carboxylesterase 1
CHN2 chimerin 2
CTSB cathepsin B
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
FOLR1 folate receptor 1 (adult)
GCLC glutamate-cysteine ligase, catalytic subunit
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA10 homeobox A10
IER3 immediate early response 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
LY75 lymphocyte antigen 75
MAP2K6 mitogen-activated protein kinase kinase 6
MSMO1 methylsterol monooxygenase 1
NET1 neuroepithelial cell transforming 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLAC8 placenta-specific 8
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB31 RAB31, member RAS oncogene family
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SORD sorbitol dehydrogenase
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TNS3 tensin 3
TSPAN5 tetraspanin 5
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AUTS2 autism susceptibility candidate 2
C1ORF106 chromosome 1 open reading frame 106
CCND2 cyclin D2
CDC25A cell division cycle 25A
CRELD2 cysteine-rich with EGF-like domains 2
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL11 chemokine (C-X-C motif) ligand 11
DPYSL3 dihydropyrimidinase-like 3
DSE dermatan sulfate epimerase
HOMER3 homer scaffolding protein 3
IDH3B isocitrate dehydrogenase 3 (NAD+) beta
PDE4B phosphodiesterase 4B, cAMP-specific
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PSPH phosphoserine phosphatase
S100A8 S100 calcium binding protein A8
SDC1 syndecan 1
SIRPA signal-regulatory protein alpha
SNX7 sorting nexin 7
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TYMS thymidylate synthetase
UBE2J1 ubiquitin-conjugating enzyme E2, J1