BRD-K48803730_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K48803730_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ARID5B AT rich interactive domain 5B (MRF1-like)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CAV1 caveolin 1, caveolae protein, 22kDa
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CD200 CD200 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLEC2B C-type lectin domain family 2, member B
COL5A2 collagen, type V, alpha 2
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CSRP2 cysteine and glycine-rich protein 2
CTSH cathepsin H
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
DHRS3 dehydrogenase/reductase (SDR family) member 3
GPNMB glycoprotein (transmembrane) nmb
GPRC5B G protein-coupled receptor, class C, group 5, member B
HIST1H2BG histone cluster 1, H2bg
HK1 hexokinase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IDO1 indoleamine 2,3-dioxygenase 1
IFI16 interferon, gamma-inducible protein 16
IFITM1 interferon induced transmembrane protein 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN2 lipocalin 2
LDOC1 leucine zipper, down-regulated in cancer 1
LEF1 lymphoid enhancer-binding factor 1
LPAR6 lysophosphatidic acid receptor 6
LRRC17 leucine rich repeat containing 17
MEF2C myocyte enhancer factor 2C
MUC1 mucin 1, cell surface associated
MZB1 marginal zone B and B1 cell-specific protein
PIP prolactin-induced protein
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
S100A9 S100 calcium binding protein A9
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SCPEP1 serine carboxypeptidase 1
SELENBP1 selenium binding protein 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB2 tribbles pseudokinase 2
TRIM2 tripartite motif containing 2
VSNL1 visinin-like 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AKAP12 A kinase (PRKA) anchor protein 12
BEX1 brain expressed, X-linked 1
CHMP4A charged multivesicular body protein 4A
COCH cochlin
CST3 cystatin C
CYR61 cysteine-rich, angiogenic inducer, 61
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLC1 DLC1 Rho GTPase activating protein
DUSP1 dual specificity phosphatase 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPN2 epsin 2
FASTKD5 FAST kinase domains 5
GNAS GNAS complex locus
GSTM3 glutathione S-transferase mu 3 (brain)
KDM5D lysine (K)-specific demethylase 5D
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGEA1 melanoma antigen family A1
MAGEA3 melanoma antigen family A3
NUP98 nucleoporin 98kDa
PDE10A phosphodiesterase 10A
PLAC8 placenta-specific 8
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RBP4 retinol binding protein 4, plasma
RET ret proto-oncogene
RPS27L ribosomal protein S27-like
SCG2 secretogranin II
TFPI2 tissue factor pathway inhibitor 2