BRD-K48488978_YM-201636_MDAMB231_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K48488978_YM-201636_MDAMB231_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
ALDOC aldolase C, fructose-bisphosphate
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CPVL carboxypeptidase, vitellogenic-like
CTSH cathepsin H
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DDR1 discoidin domain receptor tyrosine kinase 1
DHCR24 24-dehydrocholesterol reductase
DTNA dystrobrevin, alpha
GAA glucosidase, alpha; acid
GNPDA1 glucosamine-6-phosphate deaminase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGF2R insulin-like growth factor 2 receptor
IRS2 insulin receptor substrate 2
LDLR low density lipoprotein receptor
LPCAT1 lysophosphatidylcholine acyltransferase 1
LY96 lymphocyte antigen 96
METTL7A methyltransferase like 7A
NIPSNAP1 nipsnap homolog 1 (C. elegans)
ORAI3 ORAI calcium release-activated calcium modulator 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
QPRT quinolinate phosphoribosyltransferase
RORA RAR-related orphan receptor A
S100P S100 calcium binding protein P
SC5D sterol-C5-desaturase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLPI secretory leukocyte peptidase inhibitor
SPINT1 serine peptidase inhibitor, Kunitz type 1
SQLE squalene epoxidase
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPP1 tripeptidyl peptidase I
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
CAV1 caveolin 1, caveolae protein, 22kDa
CENPU centromere protein U
DLC1 DLC1 Rho GTPase activating protein
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EYA2 EYA transcriptional coactivator and phosphatase 2
FEN1 flap structure-specific endonuclease 1
FHL2 four and a half LIM domains 2
ITGA6 integrin, alpha 6
NRG1 neuregulin 1
ODC1 ornithine decarboxylase 1
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
STMN1 stathmin 1
TYMS thymidylate synthetase
ZWINT ZW10 interacting kinetochore protein