BRD-K48488978_YM-201636_MCF10A_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K48488978_YM-201636_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANXA4 annexin A4
CAPG capping protein (actin filament), gelsolin-like
CCNG2 cyclin G2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CETN2 centrin, EF-hand protein, 2
DSP desmoplakin
EIF5A eukaryotic translation initiation factor 5A
G6PD glucose-6-phosphate dehydrogenase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
LGALS1 lectin, galactoside-binding, soluble, 1
LYZ lysozyme
RAB2A RAB2A, member RAS oncogene family
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
CDC7 cell division cycle 7
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHD7 chromodomain helicase DNA binding protein 7
CLEC11A C-type lectin domain family 11, member A
COL3A1 collagen, type III, alpha 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
E2F2 E2F transcription factor 2
EIF5 eukaryotic translation initiation factor 5
EREG epiregulin
F13A1 coagulation factor XIII, A1 polypeptide
FKBP11 FK506 binding protein 11, 19 kDa
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KRT23 keratin 23, type I
LEF1 lymphoid enhancer-binding factor 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NELL2 NEL-like 2 (chicken)
PTN pleiotrophin
SCG5 secretogranin V
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
SPRED2 sprouty-related, EVH1 domain containing 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
ZDHHC6 zinc finger, DHHC-type containing 6