BRD-K47983010_BX-795_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

100 genes differentially expressed following the BRD-K47983010_BX-795_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANXA4 annexin A4
AQP1 aquaporin 1 (Colton blood group)
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CFD complement factor D (adipsin)
CKM creatine kinase, muscle
CLC Charcot-Leyden crystal galectin
CLIC3 chloride intracellular channel 3
CNOT4 CCR4-NOT transcription complex, subunit 4
CRIP2 cysteine-rich protein 2
CSTA cystatin A (stefin A)
CTSD cathepsin D
DGKA diacylglycerol kinase, alpha 80kDa
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPP4 dipeptidyl-peptidase 4
DSP desmoplakin
EGR2 early growth response 2
ELANE elastase, neutrophil expressed
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FHL1 four and a half LIM domains 1
IL13RA1 interleukin 13 receptor, alpha 1
KLHL41 kelch-like family member 41
KRT18 keratin 18, type I
KRT19 keratin 19, type I
LDB3 LIM domain binding 3
MB myoglobin
MBNL2 muscleblind-like splicing regulator 2
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MYBPC1 myosin binding protein C, slow type
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYOF myoferlin
MYOT myotilin
NEB nebulin
PDGFC platelet derived growth factor C
PEG3 paternally expressed 3
PKP1 plakophilin 1
RAB29 RAB29, member RAS oncogene family
RHOBTB3 Rho-related BTB domain containing 3
RPS5 ribosomal protein S5
S100A10 S100 calcium binding protein A10
S100P S100 calcium binding protein P
SELE selectin E
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH3YL1 SH3 and SYLF domain containing 1
SOX9 SRY (sex determining region Y)-box 9
SRSF6 serine/arginine-rich splicing factor 6
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TARP TCR gamma alternate reading frame protein
TCTN1 tectonic family member 1
TNNC1 troponin C type 1 (slow)
TNNC2 troponin C type 2 (fast)
TNNT1 troponin T type 1 (skeletal, slow)
TST thiosulfate sulfurtransferase (rhodanese)
TTN titin

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BASP1 brain abundant, membrane attached signal protein 1
BIRC5 baculoviral IAP repeat containing 5
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BPHL biphenyl hydrolase-like (serine hydrolase)
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CD24 CD24 molecule
CD300A CD300a molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
CNN3 calponin 3, acidic
CSRP2 cysteine and glycine-rich protein 2
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
EPHA3 EPH receptor A3
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FKBP1A FK506 binding protein 1A, 12kDa
IGFBP3 insulin-like growth factor binding protein 3
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
LAPTM5 lysosomal protein transmembrane 5
LDLR low density lipoprotein receptor
LEFTY2 left-right determination factor 2
LOX lysyl oxidase
MAGEA3 melanoma antigen family A3
MSN moesin
NID1 nidogen 1
OXA1L oxidase (cytochrome c) assembly 1-like
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PROM1 prominin 1
RHOB ras homolog family member B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
TDO2 tryptophan 2,3-dioxygenase
TNC tenascin C
TPM4 tropomyosin 4
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon